ArticleNigerian medical journal : journal of the Nigeria Medical Association2014
Intravenous paracetamol versus intramuscular pethidine in relief of labour pain in primigravid women.
Article in Nigerian medical journal : journal of the Nigeria Medical Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Parenteral opioids for maternal pain management in labour.The Cochrane database of systematic reviews · 2018Pooled it
- Comparison of intravenous paracetamol infusion versus intramuscular tramadol as labor analgesia: a randomized control trial.Archives of gynecology and obstetrics · 2023Trial
- Oral acetaminophen as an adjunct to continuous epidural infusion and patient-controlled epidural analgesia in laboring parturients: a randomized controlled trial.Journal of anesthesia · 2021Trial
- Pethidine in Low Doses versus Dipyrone for Pain Relief in Labor: A Randomized Controlled Trial.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2019Trial
- Comparison of Pain Score and Complications Following Acetaminophen and Pethidine Injection During Vaginal Delivery: A Double-blind Clinical Trial.Oman medical journal · 2021Article
- "We know it's labour pain, so we don't do anything": healthcare provider's knowledge and attitudes regarding the provision of pain relief during labour and after childbirth.BMC pregnancy and childbirth · 2018Article
- Comments on: Is Pethidine Safe during Labor? Systematic Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2018Article
- A Randomized Controlled Trial Comparing Use of Enthonox With Pethidine for Pain Relief in Primigravid Women During the Active Phase of Labor.Anesthesiology and pain medicine · 2016Article
- Efficacy of Intravenous Infusion of Acetaminophen for Intrapartum Analgesia.Journal of clinical and diagnostic research : JCDR · 2016Article
- Intravenous paracetamol infusion versus intramuscular tramadol as an intrapartum labor analgesic.Journal of obstetrics and gynaecology of India · 2015Article
- Medical treatment of allergy in children with recurrent or chronic sinusitis.Nigerian medical journal : journal of the Nigeria Medical Association · 2014Article
- Effects of high versus low-dose atorvastatin on high sensitive C-reactive protein in acute coronary syndrome.Nigerian medical journal : journal of the Nigeria Medical Association · 2014Article
- A COMPARATIVE STUDY OF INTRAMUSCULAR ACETAMINOPHEN VERSUS INTRAMUSCULAR PENTAZOCINE AS LABOUR ANALGESIA IN ZARIA, NORTHWESTERN NIGERIA.Journal of the West African College of SurgeonsArticle
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntramuscular pethidine is one of most common opioids used for labour analgesia. There are a number of concerns in the literature regarding the use of pethidine. The aim of this study is to compare analgesic efficacy of paracetamol with pethidine for labour pain in normal vaginal delivery. MATERIALS AND
methodsIn this single-blinded, randomised control trial, 80 primigravid singleton women with full-term pregnancy candidate for normal vaginal delivery, were entered the trial and divided in to pethidine (A) and paracetamol (B) groups. At the time of admission, age and body mass index of mother and gestational age based on last day of period were recorded. In both groups, intravenous promethazine and hyoscine were administered to each patient at the first stage of delivery. From beginning of active phase of delivery, patients in group A received 50 mg intramuscular pethidine injection. At the same time patients in group B, received an intravenous solution infusion containing 1000 mg paracetamol and 300 cc of normal saline. After child birth, average labour pain was assessed using Visual Analogue Scale (VAS) by direct questioning from patient in both groups.
resultsAfter patients' selection, 19 individual omitted during study due to exclusion criteria and finally 30 patients in paracetamol group and 31 patients in pethidine group remained to enter the trial. There was no significant difference in age and BMI of mothers between both groups (P > 0.05). Maternal age and labour duration in paracetamol group had no meaningful difference with maternal age and labour duration of patients in pethidine group (P > 0.05). The average VAS pain score was significantly lower in paracetamol comparing to that of pethidine group (8.366 out of 10, 9.612 out of 10, respectively, P < 0.001).
conclusionIt is concluded that intravenous paracetamol is more effective than intramuscular pethidine to relief labour pain in normal vaginal delivery.
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