ArticleAnnals of epidemiology2014
Declines in coronary heart disease incidence and mortality among middle-aged adults with and without diabetes.
Article in Annals of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Incidence of acute myocardial infarction in people with diabetes compared to those without diabetes: a systematic review.Systematic reviews · 2026Pooled it
- Effect of Improving Dietary Quality on Arterial Stiffness in Subjects with Type 1 and Type 2 Diabetes: A 12 Months Randomised Controlled Trial.Nutrients · 2016Trial
- Dynamic trends of ischemic heart disease mortality attributable to high low-density lipoprotein cholesterol: a joinpoint analysis and age-period-cohort analysis with predictions.Lipids in health and disease · 2024Article
- Sex-specific trends in incidence of first myocardial infarction among people with and without diabetes between 1985 and 2016 in a German region.Cardiovascular diabetology · 2024Article
- Association between diet quality indices and arterial stiffness in youth with type 1 diabetes: SEARCH for Diabetes in Youth Nutrition Ancillary Study.Journal of diabetes and its complications · 2020Article
- Article
- Refining risk in diabetes and CAD with SPECT MPI: New insights and future challenges.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Article
- Mortality Among Black Men in the USA.Journal of racial and ethnic health disparities · 2018Article
- Using Predicted Cardiovascular Disease Risk in Conjunction With Blood Pressure to Guide Antihypertensive Medication Treatment.Journal of the American College of Cardiology · 2017Review
- Association between dairy intake, lipids and vascular structure and function in diabetes.World journal of diabetes · 2017Article
- Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.Circulation · 2017Review
- Modifiable Risk Factors Versus Age on Developing High Predicted Cardiovascular Disease Risk in Blacks.Journal of the American Heart Association · 2017Article
- Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes: A cross-sectional study.World journal of diabetes · 2017Article
- Article
- Prevalence of Eligibility Criteria for the Systolic Blood Pressure Intervention Trial in US Adults Among Excluded Groups: Age <50 Years, Diabetes Mellitus, or a History of Stroke.Journal of the American Heart Association · 2016Article
- Gender Differences in Risks of Coronary Heart Disease and Stroke in Patients with Type 2 Diabetes Mellitus and Their Association with Metabolic Syndrome in China.International journal of endocrinology · 2016Article
- Differential Outcomes by Race and Ethnicity in Patients with Coronary Heart Disease: A Contemporary Review.Current cardiovascular risk reports · 2015Article
- Coronary heart disease risk factors and outcomes in the twenty-first century: findings from the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.Current hypertension reports · 2015Review
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
purposeThe purpose of the study was to investigate secular changes in coronary heart disease (CHD) incidence and mortality among adults with and without diabetes and to determine the effect of increased lipid-lowering medication use and reductions in low-density lipoprotein cholesterol (LDL-C) levels on these changes.
methodsWe analyzed data on participants aged 45 to 64 years from the Atherosclerosis Risk in Communities Study in 1987-1996 (early period) and the Reasons for Geographic and Racial Differences in Stroke Study in 2003-2009 (late period). Hazard ratios (HRs) for the association of diabetes and period with incident CHD and CHD mortality were obtained after adjustment for sociodemographics cardiovascular risk factors, lipid-lowering medication use, and LDL-C.
resultsAfter multivariable adjustment, diabetes was associated with an increased CHD risk during the early (HR = 1.99, 95% confidence interval = 1.59-2.49) and late (HR = 2.39, 95% confidence interval = 1.69-3.35) periods. CHD incidence and mortality declined between the early and late periods for individuals with and without diabetes. Increased use of lipid-lowering medication and lower LDL-C explained 33.6% and 27.2% of the decline in CHD incidence and CHD mortality, respectively, for those with diabetes.
conclusionsAlthough rates have declined, diabetes remains associated with an increased risk of CHD incidence and mortality, highlighting the need for continuing diabetes prevention and cardiovascular risk factor management.
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