ArticleBMJ open2014
Recruitment feasibility to a cohort study of endocrine and metabolic health among survivors of childhood brain tumours: a report from the Canadian study of Determinants of Endometabolic Health in ChIlDrEn (CanDECIDE).
Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.BMC public health · 2019Trial
- Early Nutritional Intervention to Promote Healthy Eating Habits in Pediatric Oncology: A Feasibility Study.Nutrients · 2022Article
- Leptin is Associated with the Tri-Ponderal Mass Index in Children: A Cross-Sectional Study.Adolescent health, medicine and therapeutics · 2021Article
- High molecular weight adiponectin levels are inversely associated with adiposity in pediatric brain tumor survivors.Scientific reports · 2020Article
- Circulating leptin levels are associated with adiposity in survivors of childhood brain tumors.Scientific reports · 2020Article
- Tri-ponderal mass index in survivors of childhood brain tumors: A cross-sectional study.Scientific reports · 2018Article
- Birth weight and body mass index z-score in childhood brain tumors: A cross-sectional study.Scientific reports · 2018Article
- Adiposity in childhood brain tumors: A report from the Canadian Study of Determinants of Endometabolic Health in Children (CanDECIDE Study).Scientific reports · 2017Article
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Authors and funding
8 authors.
Funding
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Abstract
objectivesThe aim of this study was to test the feasibility of recruitment and performance of study procedures of the Canadian Study of Determinants of Endometabolic Health in ChIlDrEn (CanDECIDE) study, which was designed to assess the determinants of endocrine and metabolic health in survivors of childhood brain tumours.
settingA single paediatric tertiary care centre in Hamilton, Ontario, Canada.
participantsWe included boys and girls, aged 5 years and older, who were lean (body mass index (BMI) below 85th centile for age and gender) or overweight/obese (BMI 85th centile or above for age and gender). We excluded children on steroids or immunosuppressant therapy, smokers and those who had an active infection for the 2 weeks prior to participation. OUTCOMES: Feasibility targets included recruitment rate of at least 50%, the consenting of 80% of participants to provide biological samples, 90% questionnaire completion rate and the ability to process biological samples from at least 80% of participants.
resultsWe approached 210 potential participants, and of the 112 (53%) who agreed to participate, 30 (26.8%) completed the study visit over 7 months. All participants agreed to fast, provide biological samples and complete the questionnaires. Sample collection was successful in 97% (29/30) of participants and laboratory procedures were feasible in 100% of collected samples. We also tested resources required for the conduct of the full study including personnel, space, laboratory equipment and procedures and determined that they are all feasible.
conclusionsRecruitment and consenting of patients for the CanDECIDE study may be feasible. However, we are considering prolonging recruitment duration and collaboration with other centres to meet recruitment targets due to lower than expected recruitment rate. Completion of questionnaires and implementation of sample processing protocols are feasible.
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