Evidence map›Paper›PMID 24969368›Full record

ArticleBMC complementary and alternative medicine2014

Identifying Chinese herbal medicine for premenstrual syndrome: implications from a nationwide database.

Hsing-Yu Chen, Ben-Shian Huang, Yi-Hsuan Lin, Irene H Su, Sien-Hung Yang, Jiun-Liang Chen, Jen-Wu Huang, Yu-Chun Chen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04189367 (A Prospective Study on the Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04189367 phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

A Prospective Study on the Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine(TCM) and Western Medicine Based on TCM Syndrome Differentiation

TypeinterventionalSponsorChang Gung Memorial HospitalRan2020 to 2022Enrolled80ConditionsBurning Mouth SyndromeArmsTraditional Chinese Medicine, Western medicine
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Hsing-Yu Chen
Ben-Shian Huang
Yi-Hsuan Lin
Irene H Su
Sien-Hung Yang
Jiun-Liang Chen
Jen-Wu Huang
Yu-Chun ChenSchool of Medicine, National Yang-Ming University, Taipei, Taiwan. yuchn.chen@googlemail.com.
Chang Gung Memorial Hospital · TWChang Gung University · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming Chiao Tung University · TWNational Yang Ming University Hospital · TWUniversity of California, San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPremenstrual syndrome (PMS) occurs in women during their reproductive age with a quite negative impact on their daily lives. Women with PMS experience a wide range of physical or psychological symptoms and seek treatment for them. Chinese herb medicine (CHM) is commonly used for PMS and the goal of this study is to investigate the prescription patterns of CHM for PMS by using a nationwide database.

methodsPrescriptions of CHM were obtained from two million beneficiaries randomly sampled from the National Health Insurance Research Database, a nationwide database in Taiwan. The ICD-9 code 625.4 was used to identify patients with PMS. Association rule mining and social network analysis were used to explore both the combinations and the core treatments for PMS.

resultsDuring 1998-2011, a total of 14,312 CHM prescriptions for PMS were provided. Jia-Wei-Xiao-Yao-San (JWXYS) was the CHM which had the highest prevalence (37.5% of all prescriptions) and also the core of prescription network for PMS. For combination of two CHM, JWXYS with Cyperus rotundus L. was prescribed most frequently, 7.7% of all prescriptions, followed by JWXYS with Leonurus heterophyllus Sweet, 5.9%, and Cyperus rotundus L. with Leonurus heterophyllus Sweet, 5.6%.

conclusionsJWXYS-centered CHM combinations were most commonly prescribed for PMS. To the best of our knowledge, this is the first pharmaco-epidemiological study to review CHM treatments for PMS. However, the efficacy and safety of these commonly used CHM were still lacking. The results of this study provide valuable references for further clinical trials and bench studies.

Indexed as

Databases, FactualDrug PrescriptionsDrugs, Chinese HerbalFemaleHumansMalePhytotherapyPremenstrual SyndromeTaiwanDrugs, Chinese Herbal

Identifiers

PMID24969368
PMCPMC4099402
OpenAlexW1984198345

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.