Evidence map›Paper›PMID 24969135›Full record

ArticleDocumenta ophthalmologica. Advances in ophthalmology2014

Human flicker electroretinography using different temporal modulations at mesopic and photopic luminance levels.

Balázs Vince Nagy, Mirella Telles Salgueiro Barboni, Cristiane Maria Gomes Martins, Marcelo Fernandes da Costa, Jan Kremers, Dora Fix Ventura

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Article in Documenta ophthalmologica. Advances in ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Test-retest repeatability of the pattern electroretinogram and flicker electroretinogram.Documenta ophthalmologica. Advances in ophthalmology · 2019
    Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Balázs Vince NagyNeuroscience and Behavior, University of São Paulo, São Paulo, SP, Brazil, nagybal@gmail.com.
Mirella Telles Salgueiro Barboni
Cristiane Maria Gomes Martins
Marcelo Fernandes da Costa
Jan Kremers
Dora Fix Ventura

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectroretinographic measurement instruments allow the variation of several stimulation parameters enabling to study a wide range of retinal processes. The purpose of the present study was to measure human flicker electroretinograms (ERGs) varying temporal modulation, temporal frequency and mean luminance in the photopic and higher mesopic ranges where the change from cone to rod dominance occurs.

methodsFourteen healthy subjects (mean age = 31 ± 6) participated in this study. ERG recordings were performed with the RetiPort system (Roland Consult, Germany). The stimuli were ON and OFF sawtooth waves, square wave and sine wave. The temporal frequencies were 4 and 8 Hz. The mean luminance varied from 1 to 60 cd/m(2).

resultsThe results confirmed the possibility to distinguish between rod- and cone-dominated retinal responses when using the flicker ERG at different temporal frequencies and luminances. We have also evaluated the responses at luminance levels at which the transition between rod- and cone-dominated responses occurs. This transition between rod- and cone-dominated flicker ERG responses is indicated by a significant change in the response characteristics between 4 and 8 cd/m(2) (between 200 and 400 phot Td).

conclusionsThe findings on the transition between rod- and cone-dominated ERGs along with the demonstration of ERG responses to different temporal flicker modulations might be informative for the electrophysiologists when setting up the stimulus at mesopic and photopic luminance levels.

Indexed as

ElectroretinographyAdultColor VisionFemaleHealthy VolunteersHumansMaleMesopic VisionPhotic StimulationRetina

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.