Trial reportInternational orthopaedics2014
Patient-specific computed tomography based instrumentation in total knee arthroplasty: a prospective randomized controlled study.
Trial report in International orthopaedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 9 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Fewer femoral rotational outliers produced with CT- than with MRI-based patient-specific instrumentation in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- Patient-Specific or Conventional Instrumentations: A Meta-analysis of Randomized Controlled Trials.BioMed research international · 2020Pooled it
- Patient-specific instrumentation improved axial alignment of the femoral component, operative time and perioperative blood loss after total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Pooled it
- Favourable alignment outcomes with MRI-based patient-specific instruments in total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Pooled it
- Using Bayesian statistics to estimate the likelihood a new trial will demonstrate the efficacy of a new treatment.BMC medical research methodology · 2017Pooled it
- A comparison of short term radiological alignment outcomes of the patient specific and standard instrumentation for primary total knee arthroplasty: A systematic review and meta-analysis.Acta orthopaedica et traumatologica turcica · 2017Pooled it
- 3D-printing techniques in a medical setting: a systematic literature review.Biomedical engineering online · 2016Pooled it
- Evaluation of the accuracy of patient-specific cutting blocks for total knee arthroplasty: a meta-analysis.International orthopaedics · 2015Pooled it
- No evidence of superiority in reducing outliers of component alignment for patient-specific instrumentation for total knee arthroplasty: a systematic review.Orthopaedic surgery · 2015Pooled it
- The impact of patient-specific instrumentation on unicompartmental knee arthroplasty: a prospective randomised controlled study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018Trial
- No radiological and clinical advantages with patient-specific positioning guides in total knee replacement.Acta orthopaedica · 2018Trial
- Patient-Specific CT-Based Instrumentation versus Conventional Instrumentation in Total Knee Arthroplasty: A Prospective Randomized Controlled Study on Clinical Outcomes and In-Hospital Data.BioMed research international · 2015Trial
- Comparison of the accuracy and efficacy of different assistive techniques in primary total knee arthroplasty: A network meta-analysis.Journal of experimental orthopaedics · 2024Article
- Development and Validation of an Artificial Intelligence Preoperative Planning and Patient-Specific Instrumentation System for Total Knee Arthroplasty.Bioengineering (Basel, Switzerland) · 2023Article
- Establishing a New Patient-Specific Implantation Technique for Total Ankle Replacement: An In Vitro Study.Foot & ankle specialist · 2023Article
- Patient-specific instrumentation for total knee arthroplasty improves reproducibility in the planned rotational positioning of the tibial component.Journal of orthopaedic surgery and research · 2022Article
- Correlation between component alignment and short-term clinical outcomes after total knee arthroplasty.Frontiers in surgery · 2022Article
- Patient-Specific Instrumentation Accuracy Evaluated with 3D Virtual Models.Journal of clinical medicine · 2021Article
- Accuracy of tibial cuts with patient-specific instrumentation is not influenced by the surgeon's level of experience.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Article
- Pre-operative radiological measurement of femoral rotation for prosthetic positioning in total knee arthroplasty.International orthopaedics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to compare radiological results of total knee arthroplasties (TKAs) performed with patient-specific computed tomography (CT)-based instrumentation and conventional technique. The main study hypothesis was that CT-based patient-specific instrumentation (PSI) increases the accuracy of TKA.
methodsA prospective, randomized controlled trial was carried out between January and December 2011. A group of 112 patients who met the inclusion and exclusion criteria were enrolled in this study and randomly assigned to an experimental or control group. The experimental group comprised 52 patients operated on with the aid of the Signature CT-based implant positioning system. The control group consisted of 60 patients operated on using conventional instrumentation. The radiographic evaluation of implant positioning and overall coronal alignment was performed 12 months after the surgery by using standing anteroposterior radiographs of the entire lower limb and standard lateral radiographs.
resultsOf the 112 patients initially enrolled for the study, 95 were included in the subsequent analyses. There were no statistically significant differences between groups in respect to coronal and sagittal component positioning and overall coronal alignment, except for frontal tibial component positioning. For this parameter, better results were obtained in the control group, with borderline statistical significance.
conclusionsOur study did not reveal superiority of the CT-based PSI system over conventional instrumentation. Further high-quality investigations of patient-specific systems are absolutely indispensable to assess their utility for TKA. In our opinion, the surgeon applying PSI technology is required to have advanced knowledge and considerable experience with the conventional method.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.