Evidence map›Paper›PMID 24968746›Full record

ArticleObesity surgery2015

Sleeve gastrectomy is a safe and efficient procedure in HIV patients with morbid obesity: a case series with results in weight loss, comorbidity evolution, CD4 count, and viral load.

Marinos Fysekidis, Régis Cohen, Mohamed Bekheit, Joseph Chebib, Abdelghani Boussairi, Hélène Bihan, Marie Aude Khuong, Laurent Finkielsztejn, Gabriela Mendoza, Sophie Abgrall and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Outcomes of Bariatric Surgery in People With Human Immunodeficiency Virus: A Retrospective Analysis From the ATHENA Cohort.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  3. Review
  4. Article
  5. Medication management and pharmacokinetic changes after bariatric surgery.Canadian family physician Medecin de famille canadien · 2020
    Review
  6. Canadian family physician Medecin de famille canadien · 2020
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Marinos FysekidisService d'Endocrinologie, Diabétologie et Maladies Métaboliques, Hôpital Avicenne, Paris XIII, 93009, Bobigny, France.
Régis Cohen
Mohamed Bekheit
Joseph Chebib
Abdelghani Boussairi
Hélène Bihan
Marie Aude Khuong
Laurent Finkielsztejn
Gabriela Mendoza
Sophie Abgrall
Djiba Condé
Jean Marc Catheline
Centre Hospitalier Saint-Denis · FRHôpital Avicenne · FRCentre Hospitalier Intercommunal André Grégoire Montreuil · FRHôpital Cochin · FRUniversité Sorbonne Paris Nord · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy and safety of bariatric surgery have been poorly studied in patients affected with HIV. Although sleeve gastrectomy (SG) is the most widely used procedure in many countries, most of the published literature reported results with the gastric bypass (GBP) procedure on morbidly obese HIV patients.

methodsWe have evaluated retrospectively, in eight consecutive patients who underwent a SG, its effect in weight loss and its impact on the treatment and on the markers of HIV infection.

resultsSeven out of eight patients were females. The mean age was 46 years, with a median preoperative BMI of 42 kg/m(2). The mean duration of HIV infection and CD4 cell count were 13.4 years and 457 cells/mm(3), respectively. The mean weight loss was 37 kg in 20 months, the excess BMI loss was 80.8 ± 30.9 %, and the excess weight loss is 81.5 ± 28.9 % with one minor complication. CD4 counts were unchanged. Three patients had therapy modifications that were unrelated to bariatric surgery. Two patients had a therapeutic drug monitoring before and after the intervention. Plasma concentrations remained in therapeutic levels after the SG. Most comorbidities disappeared postoperatively, decreasing the cardiovascular risk.

conclusionsThe sleeve gastrectomy was safe and effective with no consequences on CD4 counts and viral load in HIV-affected obese patients. It should be considered as a part of the treatment in morbidly obese HIV patients.

Indexed as

AdultBariatric SurgeryCardiovascular DiseasesCD4 Lymphocyte CountComorbidityFemaleFollow-Up StudiesGastrectomyHIV InfectionsHumansLaparoscopyMaleMiddle AgedObesity, MorbidRetrospective StudiesRisk Factors

Identifiers

PMID24968746
OpenAlexW2073763566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.