Evidence map›Paper›PMID 24967416›Full record

ReviewBioMed research international2014

Novel biomarkers of abdominal aortic aneurysm disease: identifying gaps and dispelling misperceptions.

Demetrios Moris, Eleftherios Mantonakis, Efthymios Avgerinos, Marinos Makris, Chris Bakoyiannis, Emmanuel Pikoulis, Sotirios Georgopoulos

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  7. Non-Coding RNAs as Blood-Based Biomarkers in Cardiovascular Disease.International journal of molecular sciences · 2020
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Demetrios MorisFirst Department of Surgery, Vascular Unit, "Laiko" General Hospital, National and Kapodistrian University of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Eleftherios MantonakisFirst Department of Surgery, Vascular Unit, "Laiko" General Hospital, National and Kapodistrian University of Athens, Agiou Thoma 17, 11527 Athens, Greece.ORCID 0000-0003-3640-6881
Efthymios AvgerinosDivision of Vascular Surgery, University of Pittsburgh, Pittsburgh, PA 15213-2582, USA.
Marinos MakrisImperial College, London SW7 2AZ, UK.
Chris BakoyiannisFirst Department of Surgery, Vascular Unit, "Laiko" General Hospital, National and Kapodistrian University of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Emmanuel PikoulisFirst Department of Surgery, Vascular Unit, "Laiko" General Hospital, National and Kapodistrian University of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Sotirios GeorgopoulosFirst Department of Surgery, Vascular Unit, "Laiko" General Hospital, National and Kapodistrian University of Athens, Agiou Thoma 17, 11527 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is a prevalent and potentially life-threatening disease. Early detection by screening programs and subsequent surveillance has been shown to be effective at reducing the risk of mortality due to aneurysm rupture. The aim of this review is to summarize the developments in the literature concerning the latest biomarkers (from 2008 to date) and their potential screening and therapeutic values. Our search included human studies in English and found numerous novel biomarkers under research, which were categorized in 6 groups. Most of these studies are either experimental or hampered by their low numbers of patients. We concluded that currently no specific laboratory markers allow screeing for the disease and monitoring its progression or the results of treatment. Further studies and studies in larger patient groups are required in order to validate biomarkers as cost-effective tools in the AAA disease.

Indexed as

Aortic Aneurysm, AbdominalBiomarkersFemaleHumansMaleBiomarkers

Identifiers

PMID24967416
PMCPMC4055358

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.