ArticleBioMed research international2014
Antidiabetic activity of Artemisia amygdalina Decne in streptozotocin induced diabetic rats.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- Investigating Ayurvedic Strategies: An In-Depth Examination of Managing Diabetes across Different Types.Current diabetes reviews · 2025Review
- Efficacy of oral insulin nanoparticles for the management of hyperglycemia in a rat model of diabetes induced with streptozotocin.Journal of medicine and life · 2024Article
- In Vitro Assessment of the Antidiabetic and Anti-Inflammatory Potential ofMolecules (Basel, Switzerland) · 2023Article
- Therapeutic Effect of P-Cymene on Lipid Profile, Liver Enzyme, and Akt/Mtor Pathway in Streptozotocin-Induced Diabetes Mellitus in Wistar Rats.Journal of obesity · 2022Article
- Possible Synergistic Antidiabetic Effects of QuantifiedBiology · 2021Article
- Phytochemistry and pharmacological activity of the genus artemisia.Archives of pharmacal research · 2021Review
- Natural antioxidants for neuroinflammatory disorders and possible involvement of Nrf2 pathway: A review.Heliyon · 2021Review
- Phytochemical Screening and Antidiabetic, Antihyperlipidemic, and Antioxidant Effects ofFrontiers in pharmacology · 2021Article
- Modulation of reproductive dysfunctions associated with streptozocin-induced diabetes by Artemisia judaica extract in rats fed a high-fat diet.Molecular biology reports · 2020Article
- Artemether Regulates Metaflammation to Improve Glycolipid Metabolism in db/db Mice.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Improved Production of Industrially Important Essential Oils Through Elicitation in the Adventitious Roots ofPlants (Basel, Switzerland) · 2019Article
- Liver Dysfunction and Oxidative Stress in Streptozotocin-Induced Diabetic Rats: Protective Role ofJournal of pharmacopuncture · 2019Article
- Artemisia amygdalina Upregulates Nrf2 and Protects Neurons Against Oxidative Stress in Alzheimer Disease.Cellular and molecular neurobiology · 2019Article
- Effects ofVeterinary world · 2018Article
- Antidiabetic and Antiobesity Effects of Artemether in db/db Mice.BioMed research international · 2018Article
- Bioactive Phenolics of the GenusFrontiers in pharmacology · 2018Article
- Experimental Validation of Antidiabetic Potential ofIndian journal of clinical biochemistry : IJCB · 2017Article
- Article
- Toxicological evaluations ofToxicology reports · 2015Article
- Lespedeza davurica (Lax.) Schindl. extract protects against cytokine-induced β-cell damage and streptozotocin-induced diabetes.BioMed research international · 2015Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artemisia species have been extensively used for the management of diabetes in folklore medicine. The current study was designed to investigate the antidiabetic and antihyperlipidemic effects of Artemisia amygdalina. Petroleum ether, ethyl acetate, methanol, and hydroethanolic extracts of Artemisia amygdalina were tested for their antidiabetic potentials in diabetic rats. The effect of extracts was observed by checking the biochemical, physiological, and histopathological parameters in diabetic rats. The hydroethanolic and methanolic extracts each at doses of 250 and 500 mg/kg b. w significantly reduced glucose levels in diabetic rats. The other biochemical parameters like cholesterol, triglycerides, low density lipoproteins (LDL), serum creatinine, serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), and alkaline phosphatise (ALP), were found to be reduced by the hydroethanolic and methanolic extracts. The extracts also showed reduction in the feed and water consumption of diabetic rats when compared with the diabetic control. The histopathological results of treated groups showed the regenerative/protective effect on β -cells of pancreas in diabetic rats. The current study revealed the antidiabetic potential of Artemisia amygdalina being effective in hyperglycemia and that it can effectively protect against other metabolic aberrations caused by diabetes in rats, which seems to validate its therapeutic traditional use.
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