ReviewISRN neuroscience2013
Nonsocial functions of hypothalamic oxytocin.
Review in ISRN neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 106 citations in OpenAlex.
- Genetic and epigenetic signatures associated with plasma oxytocin levels in children and adolescents with autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2023Trial
- An epistasis between dopaminergic and oxytocinergic systems confers risk of post-traumatic stress disorder in a traumatized Chinese cohort.Scientific reports · 2019Trial
- MicNet: integrating spatially resolved transcriptomes and pathology images by contrastive deep neural network.Genome biology · 2026Article
- 3D reconstruction of spatial transcriptomics with spatial pattern enhanced graph convolutional neural network.bioRxiv : the preprint server for biology · 2026Article
- 3D reconstruction of spatial transcriptomics with spatial pattern enhanced graph convolutional neural network.Briefings in bioinformatics · 2026Article
- Oxytocin Protects PC12 Cells Against β-Amyloid-Induced Cell Injury.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Assessment of the Impact of SARS-CoV-2 Infection on the Sexual Function of Women, Levels of Oxytocin and Prolactin: A Prospective Cohort Study.Journal of clinical medicine · 2024Article
- Neural and behavioral evidence for oxytocin's facilitatory effects on learning in volatile and stable environments.Communications biology · 2024Article
- Genomic analysis of Tibetan ground tits identifies molecular adaptations associated with cooperative breeding.Current zoology · 2023Article
- Coregulation: A Multilevel Approach via Biology and Behavior.Children (Basel, Switzerland) · 2023Review
- Exploring a Possible Interplay between Schizophrenia, Oxytocin, and Estrogens: A Narrative Review.Brain sciences · 2023Review
- Serum Oxytocin, Cortisol and Social Behavior in Calves: A Study in the Impossible Task Paradigm.Animals : an open access journal from MDPI · 2023Article
- Oxytocin receptor DNA methylation is associated with exogenous oxytocin needs during parturition and postpartum hemorrhage.Communications medicine · 2023Article
- Oxytocin: A Multi-Functional Biomolecule with Potential Actions in Dysfunctional Conditions; From Animal Studies and Beyond.Biomolecules · 2022Review
- Socio-behavioral dysfunction in disorders of hypothalamic-pituitary involvement: The potential role of disease-induced oxytocin and vasopressin signaling deficits.Neuroscience and biobehavioral reviews · 2022Review
- The role of oxytocin in shaping complex social behaviours: possible interactions with other neuromodulators.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Adiposity and breast, endometrial, and colorectal cancer risk in postmenopausal women: Quantification of the mediating effects of leptin, C-reactive protein, fasting insulin, and estradiol.Cancer medicine · 2022Observational
- Serum Oxytocin in Cows Is Positively Correlated with Caregiver Interactions in the Impossible Task Paradigm.Animals : an open access journal from MDPI · 2022Article
- Oxytocin in Women's Health and Disease.Frontiers in endocrinology · 2022Review
- Class A and C GPCR Dimers in Neurodegenerative Diseases.Current neuropharmacology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxytocin (OXT) is a hypothalamic neuropeptide composed of nine amino acids. The functions of OXT cover a variety of social and nonsocial activity/behaviors. Therapeutic effects of OXT on aberrant social behaviors are attracting more attention, such as social memory, attachment, sexual behavior, maternal behavior, aggression, pair bonding, and trust. The nonsocial behaviors/functions of brain OXT have also received renewed attention, which covers brain development, reproduction, sex, endocrine, immune regulation, learning and memory, pain perception, energy balance, and almost all the functions of peripheral organ systems. Coordinating with brain OXT, locally produced OXT also involves the central and peripheral actions of OXT. Disorders in OXT secretion and functions can cause a series of aberrant social behaviors, such as depression, autism, and schizophrenia as well as disturbance of nonsocial behaviors/functions, such as anorexia, obesity, lactation failure, osteoporosis, diabetes, and carcinogenesis. As more and more OXT functions are identified, it is essential to provide a general view of OXT functions in order to explore the therapeutic potentials of OXT. In this review, we will focus on roles of hypothalamic OXT on central and peripheral nonsocial functions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.