Evidence map›Paper›PMID 24967249›Full record

ArticleISRN nutrition2013

Irregular Meal Timing Is Associated with Helicobacter pylori Infection and Gastritis.

Su-Lin Lim, Claudia Canavarro, Min-Htet Zaw, Feng Zhu, Wai-Chiong Loke, Yiong-Huak Chan, Khay-Guan Yeoh

Open access · greenAbstract read
In one paragraph

Article in ISRN nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Common Risk Factors in Gastrointestinal Cancers: A Narrative Review.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Review
  7. Prevalence and associated risk factors ofWorld journal of gastroenterology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Su-Lin LimDietetics Department, National University Hospital, 5 Lower Kent Ridge Road, Main Building, Level 1, Singapore 119074.
Claudia CanavarroDietetics and Nutrition Department, Alexandra Hospital, Jurong Health, Level 1, 378 Alexandra Road, Singapore 159964.
Min-Htet ZawResearch and Strategic Planning Division, Research and Evaluation Department, Health Promotion Board, 3 Second Hospital Avenue, Singapore 168937.
Feng ZhuDepartment of Gastroenterology and Hepatology, National University Hospital, 5 Lower Kent Ridge Road Tower Block, Level 10, Singapore 119074.
Wai-Chiong LokeGlobal Healthcare Practice, KPMG, 16 Raffles Quay No. 22-00, Hong Leong Building, Singapore 048581.
Yiong-Huak ChanBiostatistics Unit, Clinical Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Block MD 11, Level 1, Singapore 117597.
Khay-Guan YeohDepartment of Gastroenterology and Hepatology, National University Hospital, 5 Lower Kent Ridge Road Tower Block, Level 10, Singapore 119074.
National University Hospital · SGAlexandra Hospital · SGHealth Promotion Board · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori (HP) is associated with chronic gastritis and gastric cancer, and more than half of the world's population is chronically infected. The aim of this retrospective study was to investigate whether an irregular meal pattern is associated with increased risk of gastritis and HP infection. The study involved 323 subjects, divided into three groups as follows: subjects with HP infection and gastritis, subjects with gastritis, and a control group. Subjects were interviewed on eating habits and meal timing. Multivariate logistic regression was used to compare groups. Adjusted odds ratios (OR) were derived controlling for gender, age, stress, and probiotic consumption. Subjects who deviated from their regular meals by 2 hours or more had a significantly higher incidence of HP infection with gastritis (adjusted OR = 13.3; 95% CI 5.3-33.3; P < 0.001) and gastritis (adjusted OR = 6.1; 95% CI 2.5-15.0; P < 0.001). Subjects who deviated their meals by 2 hours or more, twice or more per week, had an adjusted OR of 6.3 and 3.5 of acquiring HP infection with gastritis (95% CI 2.6-15.2; P < 0.001) and gastritis (95% CI 1.5-8.5; P < 0.001), respectively. Frequent deviation in meal timing over a prolonged period appears associated with increased risk of developing HP infection and gastritis.

Identifiers

PMID24967249
PMCPMC4045282
OpenAlexW1505856904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.