Trial reportOxidative medicine and cellular longevity2014
Xanthine oxidase activity is associated with risk factors for cardiovascular disease and inflammatory and oxidative status markers in metabolic syndrome: effects of a single exercise session.
Trial report in Oxidative medicine and cellular longevity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 69 citations in OpenAlex.
- Impact of single anaerobic exercise on delayed activation of endothelial xanthine oxidase in men and women.Redox report : communications in free radical research · 2017Trial
- From Multidimensional Management to Mechanistic Insight: A Review of Interventions for Hyperuricemia.International journal of molecular sciences · 2026Review
- Endovascular embolization for ruptured intracranial aneurysms: efficacy and effects on oxidative stress levels.Perioperative medicine (London, England) · 2025Article
- Unraveling Metabolic Syndrome in Youth: The Obesity Epidemic's Hidden Complication.Children (Basel, Switzerland) · 2025Review
- Evaluation of the relationship between xanthine oxidase activity and metabolic syndrome in a population group in Bangladesh.Scientific reports · 2024Article
- The Combination of Hyperuricemia and Elevated High-Sensitivity C-Reactive Protein Increased the Risk of Cardiac Conduction Block.Journal of inflammation research · 2024Article
- Assessment of the relationship between serum xanthine oxidase levels and type 2 diabetes: a cross-sectional study.Scientific reports · 2022Article
- Disordered Glucose Levels Are Associated with Xanthine Oxidase Activity in Overweight Type 2 Diabetic Women.International journal of molecular sciences · 2022Article
- Review
- Inflammatory and Oxidative Stress Markers Related to Adherence to the Mediterranean Diet in Patients with Metabolic Syndrome.Antioxidants (Basel, Switzerland) · 2022Article
- The Role of Selenoprotein Tissue Homeostasis in MetS Programming: Energy Balance and Cardiometabolic Implications.Antioxidants (Basel, Switzerland) · 2022Review
- Structural features and antioxidant activities of polysaccharides from different parts ofFrontiers in pharmacology · 2022Article
- Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes.Biomedicines · 2021Article
- Hydrogen sulfide stimulates xanthine oxidoreductase conversion to nitrite reductase and formation of NO.Redox biology · 2020Article
- Body mass index is independently associated with xanthine oxidase activity in overweight/obese population.Eating and weight disorders : EWD · 2020Article
- The Role of BRG1 in Antioxidant and Redox Signaling.Oxidative medicine and cellular longevity · 2020Review
- Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retirement Longitudinal Study.Mediators of inflammation · 2020Article
- Does Serum Uric Acid Status Influence the Association Between Left Atrium Diameter and Atrial Fibrillation in Hypertension Patients?Frontiers in cardiovascular medicine · 2020Article
- Maternal selenium status is profoundly involved in metabolic fetal programming by modulating insulin resistance, oxidative balance and energy homeostasis.European journal of nutrition · 2019Article
- Nitric Oxide Products are not Associated with Metabolic Syndrome.Journal of medical biochemistry · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe main goal of the present study was to investigate the xanthine oxidase (XO) activity in metabolic syndrome in subjects submitted to a single exercise session. We also investigated parameters of oxidative and inflammatory status. MATERIALS/
methodsA case-control study (9 healthy and 8 MS volunteers) was performed to measure XO, superoxide dismutase (SOD), glutathione peroxidase activities, lipid peroxidation, high-sensitivity C-reactive protein (hsCRP) content, glucose levels, and lipid profile. Body mass indices, abdominal circumference, systolic and diastolic blood pressure, and TG levels were also determined. The exercise session consisted of 3 minutes of stretching, 3 minutes of warm-up, 30 minutes at a constant dynamic workload at a moderate intensity, and 3 minutes at a low speed. The blood samples were collected before and 15 minutes after the exercise session.
resultsSerum XO activity was higher in MS group compared to control group. SOD activity was lower in MS subjects. XO activity was correlated with SOD, abdominal circumference, body mass indices, and hsCRP. The single exercise session reduced the SOD activity in the control group.
conclusionsOur data support the association between oxidative stress and risk factors for cardiovascular diseases and suggest XO is present in the pathogenesis of metabolic syndrome.
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