ArticleEuropean journal of dentistry2014
Application of the novel method in the diagnosis and treatment of median rhomboid glossitis Candida-associated.
Article in European journal of dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 15 citations in OpenAlex.
- Median Rhomboid Glossitis of the Tongue-Associated Kissing Lesion: A Report of a Rare Case.Cureus · 2024Article
- Median Rhomboid Glossitis: A Developmental Disorder Involving the Central Part of the Tongue.Cureus · 2023Article
- Combining lexical and context features for automatic ontology extension.Journal of biomedical semantics · 2020Article
- Diagnosis of Lingual Atrophic Conditions: Associations with Local and Systemic Factors. A Descriptive Review.The open dentistry journal · 2016Article
- Enhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo.International journal of nanomedicine · 2014Article
- Black hairy tongue in a patient with amyotrophic lateral sclerosis.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this work is to demonstrate how current molecular techniques should be integrated in the diagnostic process and can have a crucial role in the management of oral fungal infections. A case of median rhomboid glossitis Candida-associated and its resolution will be described step by step. At the time of the first observation, the lesion on the surface of the tongue did not respond to the previous administration of topical antifungal agent, such a nystatin. Firstly, in order to identify the causative agent and confirm Candida albicans infection, a brushing of the lesion was performed and polymerase chain reaction analysis was carried out. In addition, deoxyribonucleic acid sequencing method, known as Pyrosequencing(®), was used in the detection of point mutations commonly associated with fluconazole resistance and consequently, in the prediction of susceptibility to azole agents. According to molecular findings, the administration of fluconazole has therefore led to resolution of the case in 2 weeks. This case highlights how the use of molecular techniques, now-a-days, can assist the clinicians to quickly obtain the report with highly accurate and precise results and appropriately support them in the diagnosis and therapeutic process.
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