Evidence map›Paper›PMID 24966530›Full record

ArticleBioinformation2014

In silico prediction of cotton (Gossypium hirsutum) encoded microRNAs targets in the genome of Cotton leaf curl Allahabad virus.

Shweta, Jawaid A Khan

Open access · hybridAbstract read
In one paragraph

Article in Bioinformation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. miR394 Acts as a Negative Regulator ofFrontiers in plant science · 2018
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

ShwetaPlant Virus Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi-110025, India.
Jawaid A KhanPlant Virus Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi-110025, India.
Jamia Millia Islamia · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cotton leaf curl Allahabad virus (CLCuAV) belongs to genus Begomovirus, family Geminiviridae. It has single stranded monopartite DNA genome transmitted by whitefly (Bemisia tabaci). MicroRNAs (miRNAs) belong to class of endogeneous small RNAs which suppress expression of genes following cleavage or translational inhibition of target messenger RNAs. They are demonstrated to be involved in a number of plant processes such as, development, biotic and abiotic stresses. Employing in silico approach, high scoring miRNA-target pairs satisfying rules of minimum free energy and maximum complementarity were selected to investigate if they possess the potential to bind the genome CLCuAV. Our results revealed that miRNA species viz., ghr-miR2950 can target all the viral genes, ghr-miR408 targets overlapping transcripts of AC1 and AC2 genes; while ghr-miR394 and ghr-miR395a and miR395d could bind overlapping transcripts of AC1 and AC4 genes. This is the first report of prediction of cotton miRNAs which have the potential to target CLCuAV genes including AC1 and AC4, involved in viral replication and gene silencing suppression, respectively.

Indexed as

BegomovirusCotton leaf curl diseaseGene regulationMicroRNARNA Interference

Identifiers

PMID24966530
PMCPMC4070032
OpenAlexW1963982136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.