Evidence map›Paper›PMID 24966518›Full record

ArticleBioinformation2014

In silico finding of Putative Cis-Acting Elements for the Tethering of Polycomb Repressive Complex2 in Human Genome.

Mohammadreza Hajjari, Mehrdad Behmanesh, Mohammad Mehdi Jahani

Open access · hybridAbstract read
In one paragraph

Article in Bioinformation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Genomics & informatics · 2017
    Article
  2. Review
  3. Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mohammadreza HajjariDepartment of Genetics, Shahid Chamran University of Ahvaz, Ahvaz, Iran ; Department of Genetics, School of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Mehrdad BehmaneshDepartment of Genetics, School of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Mohammad Mehdi JahaniDepartment of Genetics, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Shahid Chamran University of Ahvaz · IRTarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycomb Repressive Complex2 maintains a predetermined state of transcription which constitutes a cellular memory stable over many cell divisions. Since this complex acts through the regulation of chromatin structure, it is important to understand how it is recruited to chromatin. The specific target sequences of this complex such as PRE (polycomb repressive element) have not been completely recognized in human genome. In this study, we have compared the target sequences of this complex with non-target genes in tumor cell lines. Through in silico and statistical analyses, we have identified some motifs which are over-represented in target genes against non-target genes. Analyzing these motifs shows some transcription factors which are potential recruiters of Polycomb repressive complex2.

Indexed as

Epigeneticsin silico AnalysisPRC2SUZ12Transcription factors

Identifiers

PMID24966518
PMCPMC4070047
OpenAlexW1963494148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.