Evidence map›Paper›PMID 24966476›Full record

ArticleIndian journal of clinical biochemistry : IJCB2014

Hematological and biochemical parameters in apparently healthy Indian population: defining reference intervals.

Shrilekha Sairam, Suhasini Domalapalli, Sundaram Muthu, Jayanthi Swaminathan, Vivek A Ramesh, Lalitha Sekhar, Palak Pandeya, Udhaya Balasubramaniam

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

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  7. Common Hematological Reference Indices Among Healthy Reproductive Age Indian Women-Data Subset from Nationwide Study.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
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  11. Blood count reference intervals for the Brazilian adult population: National Health Survey.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023
    Article
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  18. Prevalence of Low Platelet Count and Identification of Associating Determinants and Genetic Polymorphism in Healthy Individuals of Upper Assam, India.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shrilekha SairamDepartment of Internal Medicine and Rheumatology, Apollo First Med Hospital, Chennai, 600 010 India.
Suhasini DomalapalliDepartment of Biochemistry & Therapeutic Drug Monitoring, Apollo Health City, Jubilee Hills, Hyderabad, 500 033 Andhra Pradesh India.
Sundaram MuthuApollo Hospitals Educational and Research Foundation (AHERF), No: 16 & 17, II Floor, Krishnadeep Chambers, Apollo Annexe, No 1, Wallace Garden, Thousand Lights, Chennai, 600 006 India.
Jayanthi SwaminathanApollo Hospitals Educational and Research Foundation (AHERF), No: 16 & 17, II Floor, Krishnadeep Chambers, Apollo Annexe, No 1, Wallace Garden, Thousand Lights, Chennai, 600 006 India.
Vivek A RameshApollo Hospitals Educational and Research Foundation (AHERF), No: 16 & 17, II Floor, Krishnadeep Chambers, Apollo Annexe, No 1, Wallace Garden, Thousand Lights, Chennai, 600 006 India.
Lalitha SekharDepartment of Internal Medicine, Indraprastha Apollo Hospitals, New Delhi, 110 076 India.
Palak PandeyaHealth Checkup, Apollo Hospitals International Ltd., Ahmedabad, 382428 India.
Udhaya BalasubramaniamDepartment of Preventive Health Checks, Apollo Group of Hospital, Chennai, 600 006 India.
Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical reference intervals among Indian population are poorly defined. Therefore, there is an urgent need to establish local clinical laboratory reference intervals for healthy Indian population. The present study aimed to identify the 95 % reference interval for hematological and biochemical parameters in apparently healthy Indian population. We undertook a multicentric cross-sectional study conducted at Apollo Hospitals Educational and Research Foundation across India. Of which 10,665 reference individuals identified as healthy by physicians. The 95 % of the reference distribution was estimated using 2.5th and 97.5th percentile reference limits. The 95 % reference intervals for hemoglobin (Males: 12.3-17 g/dL; Females: 9.9-14.3 g/dL), platelet count (Males: 1.3-3.8; Females: 1.3-4.2 Lakhs/µL), erythrocyte sedimentation rate (Males: 2-22; Females: 4-55 mm/h), serum uric acid in males: 3.5-8.2 mg/dL, gamma glutamyl transferase (Males: 13-61 U/L), fasting blood glucose (Males: 78-110 mg/dL), total cholesterol (Males: 115-254 mg/dL), low density lipoprotein (Males: 60-176 mg/dL) and triglycerides (Males: 55-267 mg/dL, Females: 52-207 mg/dL) were different from currently used reference values. Additionally need for gender based partitioning were observed for triglycerides and gamma glutamyl transferase. The observed findings are of clinical significance and it needs to be validated with additional community based studies.

Indexed as

HemoglobinIndiaLipoproteinsNormal valuesReference intervalsResource-limited settings

Identifiers

PMID24966476
PMCPMC4062657
OpenAlexW2006626540

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.