ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Frontal-subcortical circuits involved in reactive control and monitoring of gaze.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- Fixational saccade inhibition and pupil dilation during self-paced limb movement preparation.PloS one · 2025Article
- Altered Effective Connectivity within an Oculomotor Control Network in Unaffected Relatives of Individuals with Schizophrenia.Brain sciences · 2021Article
- Altered effective connectivity within an oculomotor control network in individuals with schizophrenia.NeuroImage. Clinical · 2021Article
- Cortical Thickness Related to Compensatory Viewing Strategies in Patients With Macular Degeneration.Frontiers in neuroscience · 2021Article
- Dissociation of Medial Frontal β-Bursts and Executive Control.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Cognitive Control of Saccadic Selection and Inhibition from within the Core Cortical Saccadic Network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Structural Thalamofrontal Hypoconnectivity Is Related to Oculomotor Corollary Discharge Dysfunction in Schizophrenia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Prefrontal AMPA receptors are involved in the effect of methylphenidate on response inhibition in rats.Acta pharmacologica Sinica · 2018Article
- Motor and Perceptual Recovery in Adult Patients with Mild Intellectual Disability.Neural plasticity · 2018Article
- Neural Basis of Cognitive Control over Movement Inhibition: Human fMRI and Primate Electrophysiology Evidence.Neuron · 2017Article
- Cortical control and performance monitoring of interrupting and redirecting movements.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Eye Control Deficits Coupled to Hand Control Deficits: Eye-Hand Incoordination in Chronic Cerebral Injury.Frontiers in neurology · 2017Article
- Disrupted Saccade Control in Chronic Cerebral Injury: Upper Motor Neuron-Like Disinhibition in the Ocular Motor System.Frontiers in neurology · 2017Article
- The mouse cortico-striatal projectome.Nature neuroscience · 2016Article
- Speed of saccade execution and inhibition associated with fractional anisotropy in distinct fronto-frontal and fronto-striatal white matter pathways.Human brain mapping · 2016Article
- Response inhibition and response monitoring in a saccadic double-step task in schizophrenia.Brain and cognition · 2015Article
- Comparative diffusion tractography of corticostriatal motor pathways reveals differences between humans and macaques.Journal of neurophysiology · 2015Article
- Cognitive control of gaze in bipolar disorder and schizophrenia.Psychiatry research · 2015Article
- Neurophysiological and neurocognitive mechanisms underlying the effects of yoga-based practices: towards a comprehensive theoretical framework.Frontiers in human neuroscience · 2015Article
- Eye Movement Deficits Are Consistent with a Staging Model of pTDP-43 Pathology in Amyotrophic Lateral Sclerosis.PloS one · 2015Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid and reactive control of movement is essential in a dynamic environment and is disrupted in several neuropsychiatric disorders. Nonhuman primate neurophysiology studies have made significant contributions to our understanding of how saccadic eye movements can be rapidly inhibited, changed, and monitored. These results highlight a frontostriatal network involved in gaze control and provide a strong basis for understanding how cognitive control of action is implemented in the human brain. The goal of the present study was to bridge human and nonhuman primate studies by investigating reactive control of eye movements during fMRI using a task that has been used in neurophysiology studies: the search-step task. This task requires a speeded response to a visual target (no-step trial). On a minority (40%) of trials, the target jumps to a new location and participants are instructed to inhibit the initially planned saccade and redirect gaze toward the new location (redirect trial). Compared with no-step trials, greater activation in a frontal oculomotor network, including frontal and supplementary eye fields (SEFs), and the striatum was observed during correctly executed redirect trials. Individual differences in stopping efficiency were related to striatal activation. Further, greater activation in SEF was in a region anterior to that activated during visually guided saccades and scaled positively with error magnitude, suggesting a prominent role in response monitoring. Combined, these data lend new evidence for a role of the striatum in reactive saccade control and further clarify the role of SEF in action inhibition and performance monitoring.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.