ArticleJournal of clinical microbiology2014
Performance of the Liaison XL Murex HIV Ab/Ag test on clinical samples representing current epidemic HIV variants.
Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Evaluation of the analytical performance of six rapid diagnostic tests for the detection of HIV-1 and 2 in Lubumbashi, Democratic Republic of Congo.The Pan African medical journal · 2025Article
- Sensitivity and specificity of the new Bio-Rad HIV screening test, Access HIV combo V2.Journal of clinical microbiology · 2024Article
- Validation study of an automated chemiluminiscence assay to detect HIV antibodies in oral fluid specimens.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Article
- The burden of non-TB lung disease presenting to TB clinics in The Gambia: preliminary data in the XpertPublic health action · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Screening for HIV infection has improved since the first immunoassays. Today, diagnosis of HIV infection can be performed with fourth-generation tests that track both the patient's antibodies and HIV antigen. The objective of this study was to evaluate the clinical sensitivity and specificity of the new DiaSorin Liaison XL Murex HIV Ab/Ag assay compared to another fourth-generation assay, the Abbott Architect HIV Ag/Ab Combo kit. This work was performed on a large panel of 900 samples, including negative samples (n = 493) and HIV-positive (n = 407) representatives of HIV-1 group M subtypes and circulating recombinant forms (CRFs), HIV-1 group O, and HIV-2 variants. The results highlight the high specificity (98.9%) and sensitivity (100%) of this new fourth-generation assay, which are consistent with its use for the screening and diagnosis of HIV infections with the current circulating strains.
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Registered trials
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