ArticlePlant, cell & environment2015
Differential expression of miRNAs and their target genes in senescing leaves and siliques: insights from deep sequencing of small RNAs and cleaved target RNAs.
Article in Plant, cell & environment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 89 citations in OpenAlex.
- Unveiling the role of epigenetics in leaf senescence: a comparative study to identify different epigenetic regulations of senescence types in barley leaves.BMC plant biology · 2024Article
- Long noncoding RNA transcriptome analysis reveals novel lncRNAs in Morus alba 'Yu-711' response to drought stress.The plant genome · 2024Article
- The miR408a-BBP-LAC3/CSD1 module regulates anthocyanin biosynthesis mediated by crosstalk between copper homeostasis and ROS homeostasis during light induction in Malus plants.Journal of advanced research · 2023Article
- Epigenetic control of plant senescence and cell death and its application in crop improvement.Frontiers in plant science · 2023Review
- The Evolution and Functional Roles ofInternational journal of molecular sciences · 2022Review
- Integrated transcriptomics and miRNAomics provide insights into the complex multi-tiered regulatory networks associated with coleoptile senescence in rice.Frontiers in plant science · 2022Article
- Leaf senescence: progression, regulation, and application.Molecular horticulture · 2021Review
- Downregulation of GeBP-like α factor by MiR827 suggests their involvement in senescence and phosphate homeostasis.BMC biology · 2021Article
- Systematic analyses of the MIR172 family members of Arabidopsis define their distinct roles in regulation of APETALA2 during floral transition.PLoS biology · 2021Article
- PAREameters: a tool for computational inference of plant miRNA-mRNA targeting rules using small RNA and degradome sequencing data.Nucleic acids research · 2020Article
- A Regulatory Network for miR156-SPL Module inInternational journal of molecular sciences · 2019Review
- Genome-Wide Transcript and Small RNA Profiling Reveals Transcriptomic Responses to Heat Stress.Plant physiology · 2019Article
- Differential expression of miRNAs and their targets in wax-deficient rapeseed.Scientific reports · 2019Article
- Micromanagement of Developmental and Stress-Induced Senescence: The Emerging Role of MicroRNAs.Genes · 2019Review
- MicroR408 regulates defense response upon wounding in sweet potato.Journal of experimental botany · 2019Article
- A Small RNA-Mediated Regulatory Network inFrontiers in plant science · 2019Article
- PAREsnip2: a tool for high-throughput prediction of small RNA targets from degradome sequencing data using configurable targeting rules.Nucleic acids research · 2018Article
- Identification of microRNAs associated with the exogenous spermidine-mediated improvement of high-temperature tolerance in cucumber seedlings (Cucumis sativus L.).BMC genomics · 2018Article
- WHIRLY1 Occupancy Affects Histone Lysine Modification andFrontiers in plant science · 2018Article
- Bioinformatics resources for deciphering the biogenesis and action pathways of plant small RNAs.Rice (New York, N.Y.) · 2017Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
MicroRNAs (miRNAs) are a class of small RNAs, which typically function by guiding cleavage of target mRNAs. They are known to play roles in a variety of plant processes including development, responses to environmental stresses and senescence. To identify senescence regulation of miRNAs in Arabidopsis thaliana, eight small RNA libraries were constructed and sequenced at four different stages of development and senescence from both leaves and siliques, resulting in more than 200 million genome-matched sequences. Parallel analysis of RNA ends libraries, which enable the large-scale examination of miRNA-guided cleavage products, were constructed and sequenced, resulting in over 750 million genome-matched sequences. These large datasets led to the identification a new senescence-inducible small RNA locus, as well as new regulation of known miRNAs and their target genes during senescence, many of which have established roles in nutrient responsiveness and cell structural integrity. In keeping with remobilization of nutrients thought to occur during senescence, many miRNAs and targets had opposite expression pattern changes between leaf and silique tissues during the progression of senescence. Taken together, these findings highlight the integral role that miRNAs may play in the remobilization of resources and alteration of cellular structure that is known to occur in senescence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.