Observational studyPain medicine (Malden, Mass.)2014
Self-loathing aspects of depression reduce postoperative opioid cessation rate.
Observational study in Pain medicine (Malden, Mass.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02571400 (Prevalence and Predictors of Prolonged Post-surgical Opioid Use), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study
Who cites it
12 citing papers in PubMed.
- A Feasibility Study of Percutaneous Peripheral Nerve Stimulation for the Treatment of Postoperative Pain Following Total Knee Arthroplasty.Neuromodulation : journal of the International Neuromodulation Society · 2019Trial
- Article
- Percutaneous Peripheral Nerve Stimulation to Control Postoperative Pain, Decrease Opioid Use, and Accelerate Functional Recovery Following Orthopedic Trauma.Military medicine · 2019Article
- Chronic Opioid Use After Surgery: Implications for Perioperative Management in the Face of the Opioid Epidemic.Anesthesia and analgesia · 2017Review
- Pain Catastrophizing Moderates Relationships between Pain Intensity and Opioid Prescription: Nonlinear Sex Differences Revealed Using a Learning Health System.Anesthesiology · 2017Observational
- The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.Pain medicine (Malden, Mass.) · 2017Article
- The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.The journal of pain · 2017Article
- Factors associated with prescription opioid misuse in a cross-sectional cohort of patients with chronic non-cancer pain.Journal of pain research · 2017Article
- Future Directions for Pain Management: Lessons from the Institute of Medicine Pain Report and the National Pain Strategy.Hand clinics · 2016Review
- Acute Pain Medicine in the United States: A Status Report.Pain medicine (Malden, Mass.) · 2015Article
- Factors Associated with Opioid Use in a Cohort of Patients Presenting for Surgery.Pain research and treatment · 2015Article
- Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
objectiveWe previously reported that increased preoperative Beck Depression Inventory II (BDI-II) scores were associated with a 47% (95% CI 24%-64%) reduction in the rate of opioid cessation following surgery. We aimed to identify the underlying factors of the BDI-II (affective/cognitive vs somatic) associated with a decreased rate of opioid cessation after surgery.
methodsWe conducted a secondary analysis of the data from a previously reported prospective, longitudinal, observational study of opioid use after five distinct surgical procedures (total hip replacement, total knee replacement, thoracotomy, mastectomy, and lumpectomy) in 107 patients. The primary endpoint was time to opioid cessation. After exploratory factor analysis of the BDI-II, mean summary scores were calculated for each identified factor. These scores were evaluated as predictors of time to opioid cessation using Cox proportional hazards regression.
resultsThe exploratory factor analysis produced three factors (self-loathing symptoms, motivational symptoms, emotional symptoms). All three factors were significant predictors in univariate analysis. Of the three identified factors of the BDI-II, only preoperative self-loathing symptoms (past failure, guilty feelings, self-dislike, self-criticalness, suicidal thoughts, worthlessness) independently predicted a significant decrease in opioid cessation rate after surgery in the multivariate analysis (HR 0.86, 95% CI 0.75-0.99, P value 0.037).
conclusionsOur results identify a set of negative cognitions predicting prolonged time to postoperative opioid cessation. Somatic symptoms captured by the BDI-II were not primarily responsible for the association between preoperative BDI-II scores and postoperative prolonged opioid use.
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