Evidence map›Paper›PMID 24964767›Full record

SynthesisNPJ primary care respiratory medicine2014

Patient-reported outcome measures for asthma: a systematic review.

Allison Worth, Victoria Hammersley, Rebecca Knibb, Bertine Flokstra-de-Blok, Audrey DunnGalvin, Samantha Walker, Anthony E J Dubois, Aziz Sheikh

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in NPJ primary care respiratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Control of Allergic Rhinitis and Asthma Test for Children (CARATkids): A systematic review and meta-analysis of its measurement properties.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Pooled it
  2. Pooled it
  3. Measuring patient experience: a systematic review to evaluate psychometric properties of patient reported experience measures (PREMs) for emergency care service provision.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2017
    Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Understanding Health Equity in Patient-Reported Outcomes.The journal of allergy and clinical immunology. In practice · 2024
    Review
  12. Article
  13. Review
  14. Airways Type-2 Related Disorders: Multiorgan, Systemic or Syndemic Disease?International journal of molecular sciences · 2024
    Review
  15. Article
  16. Barriers and facilitators of electronic patient portal uptake for asthma management.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Allison WorthAllergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK.
Victoria HammersleyAllergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK.
Rebecca KnibbDepartment of Psychology, School of Life and Health Sciences, Aston University, Birmingham, UK.
Bertine Flokstra-de-Blok1] Department of General Practice, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands [2] GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Audrey DunnGalvinDepartment of Paediatrics and Child Health, University College, Cork, Ireland.
Samantha Walker1] Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK [2] Asthma UK, Summit House, London, UK.
Anthony E J Dubois1] Department of General Practice, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands [2] Division of Paediatric Pulmonology and Paediatric Allergy, Department of Paediatrics, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Aziz Sheikh1] Allergy & Respiratory Research Group, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK [2] Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.
University of Edinburgh · GBInstitute for Asthma and Allergy · USAston University · GBUniversity College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient-reported outcome measures (PROMs) are measures of the outcome of treatment(s) reported directly by the patient or carer. There is increasing international policy interest in using these to assess the impact of clinical care.

aimsTo identify suitably validated PROMs for asthma and examine their potential for use in clinical settings.

methodsWe systematically searched MEDLINE, EMBASE and Web of Science databases from 1990 onwards to identify PROMs for asthma. These were critically appraised, then narratively synthesised. We also identified the generic PROMs commonly used alongside asthma-specific PROMs.

resultsWe identified 68 PROMs for asthma, 13 of which were selected through screening as being adequately developed to warrant full-quality appraisal: 8 for adults, 4 for children and 1 for a child's caregiver. The PROMs found to be sufficiently well validated to offer promise for use in clinical settings were the Asthma Quality of Life Questionnaire (AQLQ) and mini-AQLQ for adults, and Pediatric Asthma Quality of Life Questionnaire for children. Rhinasthma was considered promising in simultaneously assessing the impact of asthma and rhinitis in those with coexistent disease. We identified 28 generic PROMs commonly used in conjunction with asthma-specific instruments.

conclusionsWe identified asthma PROMs that offer the greatest potential for use in clinical settings. Further work is needed to assess whether these are fit-for-purpose for use in clinical practice with individual patients. In particular, there is a need to ensure these are validated for use in clinical settings, acceptable to patients, caregivers and clinicians, and yield meaningful outcomes.

Indexed as

AdultAsthmaChildHumansPatient Outcome AssessmentQuality of LifeSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID24964767
PMCPMC4373322
OpenAlexW2110890273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.