ArticlePloS one2014
The microbial detection array for detection of emerging viruses in clinical samples--a useful panmicrobial diagnostic tool.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Characterization of a MERS-related betacoronavirus in Danish brown long-eared bats (Plecotus auritus).Virology journal · 2025Article
- Unbiased Virus Detection in a Danish Zoo Using a Portable Metagenomic Sequencing System.Viruses · 2023Article
- Improvements in metagenomic virus detection by simple pretreatment methods.Journal of clinical virology plus · 2022Article
- A poly(dimethylsiloxane)-based solid-phase microchip platform for dual detection of Pseudorabies virus gD and gE antibodies.Frontiers in cellular and infection microbiology · 2022Article
- Article
- Mosquito-Borne Viruses and Insect-Specific Viruses Revealed in Field-Collected Mosquitoes by a Monitoring Tool Adapted from a Microbial Detection Array.Applied and environmental microbiology · 2019Article
- Impact of viral presence in tumor on gene expression in non-small cell lung cancer.BMC cancer · 2018Article
- Ionizing radiation exposure: hazards, prevention, and biomarker screening.Environmental science and pollution research international · 2018Article
- Fecal Microbiota Transplantation Is Associated With Reduced Morbidity and Mortality in Porcine Circovirus Associated Disease.Frontiers in microbiology · 2018Article
- Up-regulation of calreticulin in mouse liver tissues after long-term irradiation with low-dose-rate gamma rays.PloS one · 2017Article
- Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung.British journal of cancer · 2016Article
- Human pegivirus detected in a patient with severe encephalitis using a metagenomic pan-virus array.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Review
- Proteomics analysis of liver tissues from C57BL/6J mice receiving low-dose 137Cs radiation.Environmental science and pollution research international · 2016Article
- Detection of Epstein-Barr virus (EBV) in human lymphoma tissue by a novel microbial detection array.Biomarker research · 2014Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging viruses are usually endemic to tropical and sub-tropical regions of the world, but increased global travel, climate change and changes in lifestyle are believed to contribute to the spread of these viruses into new regions. Many of these viruses cause similar disease symptoms as other emerging viruses or common infections, making these unexpected pathogens difficult to diagnose. Broad-spectrum pathogen detection microarrays containing probes for all sequenced viruses and bacteria can provide rapid identification of viruses, guiding decisions about treatment and appropriate case management. We report a modified Whole Transcriptome Amplification (WTA) method that increases unbiased amplification, particular of RNA viruses. Using this modified WTA method, we tested the specificity and sensitivity of the Lawrence Livermore Microbial Detection Array (LLMDA) against a wide range of emerging viruses present in both non-clinical and clinical samples using two different microarray data analysis methods.
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