Evidence map›Paper›PMID 24963485›Full record

Trial reportBioMed research international2014

Dysfunction of affective network in post ischemic stroke depression: a resting-state functional magnetic resonance imaging study.

Peiyao Zhang, Qin Xu, Jianping Dai, Jun Wang, Ning Zhang, Yuejia Luo

Abstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Dysfunction of anterior insula in the non- affected hemisphere in patients with post- stroke depression: A resting-state fMRI study.Technology and health care : official journal of the European Society for Engineering and Medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peiyao ZhangDepartment of Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantanxili, Dongcheng District, Beijing 100050, China.
Qin XuCentre for Studies of Psychological Application, Key Laboratory of Mental Health and Cognitive Science of Guangdong Province, School of Psychology, South China Normal University, Guangzhou, China.ORCID 0000-0002-4481-3965
Jianping DaiDepartment of Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantanxili, Dongcheng District, Beijing 100050, China.ORCID 0000-0001-8957-7954
Jun WangState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China ; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.
Ning ZhangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantanxili, Dongcheng District, Beijing 100050, China.
Yuejia LuoState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China ; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, 19 Xinjiekouwai Street, Haidian District, Beijing 100875, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious studies have demonstrated that stroke characteristics and social and psychological factors jointly contribute to the development of poststroke depression (PSD). The purpose of this study was to identify altered functional connectivity (FC) of the affective network (AN) in patients with PSD and to explore the correlation between FC and the severity of PSD. MATERIALS AND

methods26 PSD patients, 24 stroke patients without depression, and 24 age-matched normal controls underwent the resting-state functional MRI (fMRI) scanning. The bilateral anterior cingulated cortices (ACCs) were selected as regions of interest (ROIs). FC was calculated and compared among the three groups. The association between FC and Hamilton Depression Rate Scale (HDRS) scores of PSD group was investigated.

resultsThe FC of the AN was disrupted in PSD patients compared to stroke patients without depression and normal controls. Moreover, the left orbital part of inferior frontal gyrus which indicated altered FC was significantly correlated with HDRS scores in PSD patients.

conclusionsDysfunction of the affective network may be one of the reasons of the development of PSD.

Indexed as

Magnetic Resonance ImagingAdultAgedBrainBrain IschemiaDepressionFemaleHumansMaleMiddle AgedNerve NetProspective StudiesRadiographyStroke

Identifiers

PMID24963485
PMCPMC4053214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.