Evidence map›Paper›PMID 24963329›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2014

Correlation between the Effects of Acupuncture at Taichong (LR3) and Functional Brain Areas: A Resting-State Functional Magnetic Resonance Imaging Study Using True versus Sham Acupuncture.

Chunxiao Wu, Shanshan Qu, Jiping Zhang, Junqi Chen, Shaoqun Zhang, Zhipeng Li, Jiarong Chen, Huailiang Ouyang, Yong Huang, Chunzhi Tang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Acupoints for Tension-Type Headache: A Literature Study Based on Data Mining Technology.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  8. Resting-State fMRI in Studies of Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Status of the Quality Control in Acupuncture-Neuroimaging Studies.Evidence-based complementary and alternative medicine : eCAM · 2016
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Actigraph evaluation of acupuncture for treating restless legs syndrome.Evidence-based complementary and alternative medicine : eCAM · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chunxiao WuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.ORCID 0000-0002-8637-5545
Shanshan QuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Jiping ZhangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Junqi ChenSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Shaoqun ZhangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Zhipeng LiFirst Clinical School, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Jiarong ChenFirst Clinical School, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Huailiang OuyangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Yong HuangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
Chunzhi TangClinical Medical College of Acupuncture, Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province 510405, China.
Southern Medical University · CNGuangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional magnetic resonance imaging (fMRI) has been shown to detect the specificity of acupuncture points, as proved by numerous studies. In this study, resting-state fMRI was used to observe brain areas activated by acupuncture at the Taichong (LR3) acupoint. A total of 15 healthy subjects received brain resting-state fMRI before acupuncture and after sham and true acupuncture, respectively, at LR3. Image data processing was performed using Data Processing Assistant for Resting-State fMRI and REST software. The combination of amplitude of low-frequency fluctuation (ALFF) and regional homogeneity (ReHo) was used to analyze the changes in brain function during sham and true acupuncture. Acupuncture at LR3 can specifically activate or deactivate brain areas related to vision, movement, sensation, emotion, and analgesia. The specific alterations in the anterior cingulate gyrus, thalamus, and cerebellar posterior lobe have a crucial effect and provide a valuable reference. Sham acupuncture has a certain effect on psychological processes and does not affect brain areas related to function.

Identifiers

PMID24963329
PMCPMC4055001
OpenAlexW1992822453

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.