ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2015
Increased cardiovascular stiffness and impaired age-related functional status.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Cardiovascular impact of near complete estrogen deprivation in premenopausal women with breast cancer: The CROWN study.American heart journal · 2024Article
- Article
- Trends in the Incidence of Activities of Daily Living Disability Among Chinese Older Adults From 2002 to 2014.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Noncardiac-Related Morbidity, Mobility Limitation, and Outcomes in Older Adults With Heart Failure.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Trends in Incidence of Disability in Activities of Daily Living in Chinese Older Adults: 1993-2006.Journal of the American Geriatrics Society · 2017Article
- Apolipoprotein E Genotype Linked to Spatial Gait Characteristics: Predictors of Cognitive Dual Task Gait Change.PloS one · 2016Article
- Stress: the good, the bad and the ugly?Zeitschrift fur Gerontologie und Geriatrie · 2015Article
- Trends in disability in activities of daily living among Chinese older adults, 1997-2006: the China Health and Nutrition Survey.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Our objective was to determine if increased cardiovascular (CV) stiffness is associated with disability in middle-aged and older adults at risk for congestive heart failure. CV stiffness (brachial pulse pressure/left ventricular stroke volume indexed to body surface area) and total disability (the summed assessment of activities of daily living, mobility, and instrumental activities of daily living) were measured in 445 individuals. A subset of 109 randomly selected individuals also underwent physical function testing. Total disability was associated with CV stiffness (p = .01), driven by an association with mobility (p = .005), but not activities of daily living (p = .13) or instrumental activities of daily living (p = .61). After accounting for age, these correlations remained significant for men (p = .04), but not for women. CV stiffness was also associated with increased 400-m walk time (p = .02). In middle-aged and elderly men at risk for congestive heart failure, CV stiffness is associated with decreased mobility and physical function, and increased overall disability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.