Evidence map›Paper›PMID 24963113›Full record

SynthesisDiabetes care2014

Patient preferences for noninsulin diabetes medications: a systematic review.

Tanjala S Purnell, Susan Joy, Emily Little, John F P Bridges, Nisa Maruthur

Abstract readSystematic Review
In one paragraph

Synthesis in Diabetes care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Variation in Cervical Cancer Screening Preferences among Medically Underserved Individuals in the United States: A Systematic Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Pooled it
  3. How well do discrete choice experiments predict health choices? A systematic review and meta-analysis of external validity.The European journal of health economics : HEPAC : health economics in prevention and care · 2018
    Pooled it
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  15. Perspectives and Preferences of People with Type 2 Diabetes for the Attributes of Weekly Insulin.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
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  17. Outcomes and Attributes Patients Value When Choosing Glucose-Lowering Medications: A Mixed-Methods Study.Clinical diabetes : a publication of the American Diabetes Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tanjala S PurnellDivision of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MDWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD tpurnel1@jhmi.edu.
Susan JoyDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Emily LittleDivision of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
John F P BridgesDepartment of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Nisa MaruthurDivision of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MDWelch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MDDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Funding

BEHAVIORAL RESEARCH IN HEART &VASCULAR DISEASET32HL007180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MARUTHUR, NISA M · 1985 to 2020
$11.4M
NHLBI NIH HHS 5T32 HL 007180NHLBI NIH HHS T32 HL007180
6 · The paper itself

Abstract

objectiveAn evidence-based synthesis of patient preferences for management of hyperglycemia is needed. Our objective was to systematically review patient preferences for noninsulin diabetes medications in adults with type 2 diabetes. RESEARCH DESIGN AND

methodsWe searched the PubMed, Embase, CINAHL, and EconLit databases for articles published on or before 23 January 2013. We included English-language studies of adult patients with type 2 diabetes that assessed patient preferences for diabetes medication treatment. Titles, abstracts, and articles were reviewed by at least two independent reviewers. Study data and quality were abstracted with standard protocols.

resultsOf 2,811 titles identified in our original search, 10 articles met inclusion criteria for the systematic review. Studies were conducted from 2007 to 2012 among diverse patient populations in the U.S., Sweden, Denmark, and the U.K. Methods used to assess patient preferences included discrete choice experiments (e.g., conjoint analysis), time tradeoff exercises, standard gamble, and patient surveys. Key attributes of diabetes medication associated with patient preferences included treatment benefits (e.g., glycemic control and weight loss/control), treatment burden (e.g., administration, frequency, and cost), and side effects (e.g., weight gain, gastrointestinal effects, and hypoglycemia).

conclusionsVarious clinical and quality of life-related factors influence patient preferences for noninsulin diabetes medications. Treatment efficacy with regard to glycemic control and weight loss/control and the risk of treatment-related hypoglycemia and gastrointestinal effects are reported to be important drivers of patient treatment selections. Future work is needed to identify practical methods for incorporating patient preferences into treatment decision making and patient-centered care.

Indexed as

Patient PreferenceAdultBlood GlucoseChoice BehaviorDecision MakingDiabetes Mellitus, Type 2HumansHypoglycemic AgentsPatient-Centered CareTreatment OutcomeBlood GlucoseHypoglycemic Agents

Identifiers

PMID24963113
PMCPMC4067391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.