ArticlePhysiological reports2014
The daily rhythm of milk synthesis is dependent on the timing of feed intake in dairy cows.
Article in Physiological reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Effects of timing of abomasal infusion of fatty acids on the daily rhythms of milk synthesis and plasma hormones and metabolites in dairy cows.Journal of dairy science · 2025Article
- Comparisons of Feed Bunk Nutrient Consistency, Milk Production and Cow Behavior Between Herds Using Automated Milking Systems With or Without Automated Feeding Robots.Animals : an open access journal from MDPI · 2025Article
- Article
- Associations of Grazing and Rumination Behaviours with Performance Parameters in Spring-Calving Dairy Cows in a Pasture-Based Grazing System.Animals : an open access journal from MDPI · 2023Article
- Daily fluctuation of colonic microbiome in response to nutrient substrates in a pig model.NPJ biofilms and microbiomes · 2023Article
- Article
- Circadian clocks and their integration with metabolic and reproductive systems: our current understanding and its application to the management of dairy cows.Journal of animal science · 2022Review
- Influence of Different Lactation Stages on Circadian Rhythmicity of Metabolic Biomarkers in Dairy Cows: A Pilot Study.Animals : an open access journal from MDPI · 2021Article
- Night-restricted feeding of dairy cows modifies daily rhythms of feed intake, milk synthesis and plasma metabolites compared with day-restricted feeding.The British journal of nutrition · 2020Article
- The effects of source and concentration of dietary fiber, starch, and fatty acids on the daily patterns of feed intake, rumination, and rumen pH in dairy cows.Journal of dairy science · 2018Article
- CLOCK regulates mammary epithelial cell growth and differentiation.American journal of physiology. Regulatory, integrative and comparative physiology · 2016Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regulation of the daily rhythm of milk synthesis is important to production animals and breastfeeding, but is difficult to observe in nursing animals. The rate of food intake varies over the day and is expected to create a daily rhythm of nutrient absorption. The objective of this study was to determine if the timing of food intake entrains a daily pattern of milk synthesis. Seventeen Holstein cows were used in a crossover design. Treatments were ad libitum feeding of a total mixed ration once daily (1× fed) or fed in four equal meals every 6 h (4× fed). Cows were milked every 6 h the last 7 days of each period. There was a treatment by time of day interaction for milk and milk component yield and concentration. Milk fat and protein concentration and yield exhibited a daily rhythm and the amplitude of the rhythm was reduced in 4× fed. In addition, milk fat percent was higher in 4× fed than 1× fed at three of the four milking intervals (0.22-0.45% higher) and 4× fed increased daily milk fat yield. Treatment by time of day interactions were detected for plasma glucose, insulin, and blood urea nitrogen. These variables also fit a cosine function with a 24 h period and the amplitudes of plasma glucose, insulin, and blood urea nitrogen rhythms were decreased by 4× feeding. In conclusion, there is a circadian pattern of milk synthesis in the dairy cow that is responsive to the timing of food intake.
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