ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2014
Effects of systematic cue exposure through virtual reality on cigarette craving.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07223879 (Single Blind, Parallel Group Trial of Novel, On-Demand Virtual Reality to Amplify Practice Efficacy), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single Blind, Parallel Group Trial of Novel, On-Demand Virtual Reality to Amplify Practice Efficacy (NO VAPE) Added to Cognitive Behavioral Therapy for Nicotine Vaping Cessation
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Virtual Reality Technology Use in Cigarette Craving and Smoking Interventions (I "Virtually" Quit): Systematic Review.Journal of medical Internet research · 2021Pooled it
- Virtual Reality (VR) in Assessment and Treatment of Addictive Disorders: A Systematic Review.Frontiers in neuroscience · 2019Pooled it
- Virtual reality in the assessment, understanding, and treatment of mental health disorders.Psychological medicine · 2017Pooled it
- A novel imagery-based retrieval-extinction training for intervention in nicotine addiction.BMC medicine · 2025Trial
- Virtual reality-based cue exposure therapy reduces psychological craving in men with methamphetamine use disorder: a randomized controlled trial.Translational psychiatry · 2025Trial
- A randomized controlled experiment testing the use of virtual reality to trigger cigarette craving in people who smoke.Scientific reports · 2024Trial
- Psychophysiological Responses in Virtual Reality for Assessing Current Nicotine Use and Future Addiction Risk Among Young Adults: Protocol for a Mixed Methods Study.JMIR research protocols · 2026Article
- Comparing the effectiveness of virtual reality vs 2D display-based cue reactivity paradigms to induce nicotine-craving: a behavioral and psychophysiological study.Scientific reports · 2025Article
- Article
- Towards virtual reality exposure therapy for cocaine use disorder: A feasibility study of inducing cocaine craving through virtual reality.Addictive behaviors reports · 2024Article
- Cigarette craving in virtual reality cue exposure in abstainers and relapsed smokers.Scientific reports · 2024Article
- Craving on the move: targeting smoking memories with a novel 3MDR-smoking cessation protocol.Frontiers in psychiatry · 2024Article
- Virtual reality cue exposure therapy for tobacco relapse prevention: a comparative study with standard intervention.Psychological medicine · 2023Article
- Cue-reactivity targeted smoking cessation intervention in individuals with tobacco use disorder: a scoping review.Frontiers in psychiatry · 2023Article
- VR for Studying the Neuroscience of Emotional Responses.Current topics in behavioral neurosciences · 2023Article
- Application of Digital Medicine in Addiction.Journal of Shanghai Jiaotong University (science) · 2022Article
- Clinical Relevance of Immersive Virtual Reality in the Assessment and Treatment of Addictive Disorders: A Systematic Review and Future Perspective.Journal of clinical medicine · 2021Review
- Is Virtual Reality Cue Exposure a Promising Adjunctive Treatment for Alcohol Use Disorder?Journal of clinical medicine · 2021Review
- Cognitive behavioural therapy in virtual reality treatments across mental health conditions: a systematic review.Consortium psychiatricum · 2020Review
- Isradipine enhancement of virtual reality cue exposure for smoking cessation: Rationale and study protocol for a double-blind randomized controlled trial.Contemporary clinical trials · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
introductionCigarette cravings have been associated with less successful attempts to quit smoking and a greater likelihood of relapse after smoking cessation. Background craving refers to a relatively steady and continuous experience of craving, while cue-induced craving refers to phases of intense craving triggered by cues associated with smoking. Cue exposure treatment (CET) involves repeated exposure to stimuli associated with substance use in order to reduce craving responses. However, mixed results have been found regarding the effect of CET on both types of craving. The aim of this study was to assess the effect of systematic virtual reality cue exposure treatment (VR-CET) on background and cue-induced cravings.
methodsParticipants were 48 treatment-seeking smokers. The VR-CET consisted of prolonged exposure sessions to several interactive virtual environments. The VR-CET was applied once a week over 5 weeks. An individualized hierarchy of exposure was drawn up for each patient starting from the easiest virtual environment. Background and cue-induced cravings were recorded in each session.
resultsCue-induced craving decreased over each session as a result of prolonged exposure. VR-CET also reduced cue-induced and background cravings across the 5 sessions, showing a cumulative effect across the exposure sessions.
conclusionsOur results evidenced the utility of VR-CET in reducing both types of cigarette craving. A combination of CET through VR with psychological treatments may improve current treatments for smoking cessation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.