ReviewDocumenta ophthalmologica. Advances in ophthalmology2014
Visual electrophysiology in the clinical evaluation of optic neuritis, chiasmal tumours, achiasmia, and ocular albinism: an overview.
Review in Documenta ophthalmologica. Advances in ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nystagmus characteristics and their impact on pattern-reversal VEP in patients with albinism.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- The diagnostic value of multichannel VEPs for children without nystagmus.Documenta ophthalmologica. Advances in ophthalmology · 2025Article
- Transcorneal Electrical Stimulation Modulates Visual Pathway Function in Mice.Journal of neuroscience research · 2025Article
- ERG Responses in Albinism, Idiopathic Infantile Nystagmus, and Controls.Investigative ophthalmology & visual science · 2024Article
- Multimodal evoked potentials are useful for the diagnosis of pediatric acute disseminated encephalomyelitis.BMC pediatrics · 2024Article
- Analysis of the slope between P50 and N95 waves of the large field pattern electroretinogram as an additional indicator of ganglion cell dysfunction.Documenta ophthalmologica. Advances in ophthalmology · 2023Article
- The Role of Optical Coherence Tomography in Early Detection of Retinal Nerve Fiber Layer Damage in Pituitary Adenoma.Maedica · 2022Article
- Retrograde Optic Nerve Degeneration in Pituitary Adenoma: A Study with RE-PERG.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- The electrophysiological tests in the early detection of the visual pathway dysfunction in patients with microadenoma.Documenta ophthalmologica. Advances in ophthalmology · 2021Article
- What can visual electrophysiology tell about possible visual-field defects in paediatric patients.Eye (London, England) · 2021Review
- Pattern-onset and OFFset visual evoked potentials in the diagnosis of hemianopic field defects.Documenta ophthalmologica. Advances in ophthalmology · 2021Article
- Chromatic visual evoked potentials indicate early dysfunction of color processing in young patients with demyelinating disease.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- Occipital Petalia and Albinism: A Study of Interhemispheric VEP Asymmetries in Albinism with No Nystagmus.Journal of clinical medicine · 2019Article
- The importance of the electrophysiological tests in the early diagnosis of ganglion cells and/or optic nerve dysfunction coexisting with pituitary adenoma: an overview.Documenta ophthalmologica. Advances in ophthalmology · 2018Review
- The clinical value of the multi-channel PVEP and PERG in the diagnosis and management of the patient with pituitary adenoma: a case report.Documenta ophthalmologica. Advances in ophthalmology · 2018Article
- Visual function assessed by visually evoked potentials in optic pathway low-grade gliomas with and without neurofibromatosis type 1.Documenta ophthalmologica. Advances in ophthalmology · 2018Article
- [Optical coherence tomography as a predictor of visual recovery in patients with pituitary macroadenomas].Surgical neurology international · 2018Article
- Gender-based normative values for pattern-reversal and flash visually evoked potentials under binocular and monocular stimulation in healthy adults.Documenta ophthalmologica. Advances in ophthalmology · 2017Observational
- The changing shape of the ISCEV standard pattern onset VEP.Documenta ophthalmologica. Advances in ophthalmology · 2017Article
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1 author at 1 institution in 1 country.
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Abstract
BACKGROUND AND
methodsIn routine clinical evaluation of optic neuritis and chiasmal tumours, pattern electroretinography and visual evoked potentials (VEPs) to pattern-reversal stimulation are useful examinations. Similarly, in achiasmia and ocular albinism, VEPs to flash and pattern-onset stimulation provide relevant information.
resultsThe role of visual electrophysiology in these diseases is to assess potential dysfunction of the visual pathway: (a) at the acute stage of optic neuritis, to determine the magnitude of conduction block of the optic nerve fibres; (b) at the clinical recovery stage of optic neuritis, to determine optic nerve conduction delay due to demyelination, and to follow possible remyelination; (c) at the recovery of optic neuritis when visual acuity does not normalise, to define loss of optic nerve fibres and retrograde degeneration of retinal ganglion cells; (d) in tumours at the chiasm, to detect abnormal conduction along the crossed and/or uncrossed fibres; and (e) in achiasmia or albinism, which are both congenital disorders associated with nystagmus, to detect achiasmia and absence of or reduced optic nerve fibre decussation at the chiasm, or to detect ocular albinism and excess of optic nerve fibre decussation at the chiasm. In optic neuritis, two recent examinations have been used to detect retrograde axonal degeneration: photopic negative response of the electroretinogram, to assess dysfunction of ganglion cell axons; and optic coherence tomography, to measure thinning of the retinal nerve fibre layer. In optic neuritis, multifocal VEPs provide a promising clinical examination, because this can show areas that are associated with normal or abnormal optic nerve fibre function.
conclusionsVisual electrophysiology defines function of the visual pathway and is relevant: (1) in optic neuritis, when visual acuity does not recover well; (2) in tumours of the chiasm with normal visual fields, as in paediatric patients who cannot adequately perform perimetry; and (3) in children with congenital nystagmus and suspected achiasmia or ocular albinism.
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