ArticleScientific reports2014
Quorum quenching bacteria Bacillus sp. QSI-1 protect zebrafish (Danio rerio) from Aeromonas hydrophila infection.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- The chemotaxis disruption of Aeromonas veronii by Lactococcus lactis and its probiotic effect on loach (Misgurnus anguillicaudatus).Archives of microbiology · 2026Article
- Biotechnological Potential of Quorum Quenching Bacterial Strains Isolated fromAnimals : an open access journal from MDPI · 2026Article
- Quorum-quenching for bacterial pathogen control and health management in aquaculture: mechanisms, applications, current status and future prospects.Frontiers in systems biology · 2026Review
- Genomic insights, determination of quorum quenching potential of a beta-lactamase enzyme from Chromohalobacter sp. strain D23 against Aeromonas hydrophila and molecular docking study.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Quorum Quenching Approaches against Bacterial-Biofilm-Induced Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2024Review
- Antibacterial Mechanisms and Antivirulence Activities of Oridonin against PathogenicMicroorganisms · 2024Article
- Synbiotic Agents and Their Active Components for Sustainable Aquaculture: Concepts, Action Mechanisms, and Applications.Biology · 2023Review
- Evaluation ofMicroorganisms · 2023Article
- Bacillus subtilis KM0 Impacts gut Microbiota Profile and Transcription of Genes Related to Transcellular Transport in Zebrafish (Danio rerio).Current microbiology · 2023Article
- Bacillus Co-culture Inhibits Quorum Sensing in Pseudomonas aeruginosa.Current microbiology · 2023Article
- The Role of Quorum Sensing Molecules in Bacterial-Plant Interactions.Metabolites · 2023Review
- Quorum-Sensing Inhibition by Gram-Positive Bacteria.Microorganisms · 2022Review
- Quorum sensing in human gut and food microbiomes: Significance and potential for therapeutic targeting.Frontiers in microbiology · 2022Review
- Article
- Attenuation ofAntibiotics (Basel, Switzerland) · 2021Article
- Isolation and Characterization of Fish-Gut Bacillus spp. as Source of Natural Antimicrobial Compounds to Fight Aquaculture Bacterial Diseases.Marine biotechnology (New York, N.Y.) · 2021Article
- Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection.The ISME journal · 2021Article
- Mechanisms Used by Probiotics to Confer Pathogen Resistance to Teleost Fish.Frontiers in immunology · 2021Review
- Heterologous expression of AHL lactonase AiiK by Lactobacillus casei MCJΔ1 with great quorum quenching ability against Aeromonas hydrophila AH-1 and AH-4.Microbial cell factories · 2020Article
- Quorum quenching potential of Enterococcus faecium QQ12 isolated from gastrointestinal tract of Oreochromis niloticus and its application as a probiotic for the control of Aeromonas hydrophila infection in goldfish Carassius auratus (Linnaeus 1758).Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
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4 authors.
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Abstract
Quorum Sensing (QS) is a bacterial regulatory mechanism, which is responsible for controlling the expression of various biological macromolecules such as the virulence factors in a cell density-dependent manner. Disruption of the QS system of pathogens has been proposed as a new anti-infective strategy. Biodegradation of AHLs proves to be an efficient way to interrupt QS, since AHLs are the main family of QS autoinducers used in Gram negative bacteria. In this study, the effect of Bacillus sp. QSI-1 as an efficient quorum quencher on virulence factors production and biofilm formation of fish pathogen Aeromonas hydrophila was investigated. QSI-1 reduced the accumulation of AHLs but did not affect the growth of A. hydrophila YJ-1 when cocultured. In the result, the supernatant of QSI-1 showed significant inhibition of protease production (83.9%), hemolytic activity (77.6%) and biofilm formation (77.3%) in YJ-1. In biocontrol experiment, QSI-1 significantly reduced the pathogenicity of A. hydrophila strain YJ-1 in zebrafish (Danio rerio). The fish fed with QSI-1 was observed to have a relative percentage survival of 80.8%. Our results indicate that AHLs degrading bacteria should be considered as an alternative for antibiotics in aquaculture for the biocontrol of bacterial fish diseases.
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