Evidence map›Paper›PMID 24961796›Full record

ReviewDevelopment (Cambridge, England)2014

The roles and regulation of multicellular rosette structures during morphogenesis.

Molly J Harding, Hillary F McGraw, Alex Nechiporuk

Open access · bronzeAbstract readReview
In one paragraph

Review in Development (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 133 citations in OpenAlex.

  1. Article
  2. Article
  3. Actuation of Cell Layers in Three Dimensions.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  4. Review
  5. Review
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  15. The Geometric Basis of Epithelial Convergent Extension.bioRxiv : the preprint server for biology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Molly J HardingDepartment of Cell and Developmental Biology, Oregon Health & Science University, Portland, OR 97239, USA Neuroscience Graduate Program, Oregon Health & Science University, Portland, OR 97239, USA.
Hillary F McGrawDepartment of Cell and Developmental Biology, Oregon Health & Science University, Portland, OR 97239, USA.
Alex NechiporukDepartment of Cell and Developmental Biology, Oregon Health & Science University, Portland, OR 97239, USA nechipor@ohsu.edu.
Oregon Health & Science University · US

Funding

Genetic analyses of axon transport and microtubule dynamics in ZebrafishR01HD072844 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI NECHIPORUK, ALEX · 2012 to 2016
$1.6M
NICHD NIH HHS R01 HD072844
6 · The paper itself

Abstract

Multicellular rosettes have recently been appreciated as important cellular intermediates that are observed during the formation of diverse organ systems. These rosettes are polarized, transient epithelial structures that sometimes recapitulate the form of the adult organ. Rosette formation has been studied in various developmental contexts, such as in the zebrafish lateral line primordium, the vertebrate pancreas, the Drosophila epithelium and retina, as well as in the adult neural stem cell niche. These studies have revealed that the cytoskeletal rearrangements responsible for rosette formation appear to be conserved. By contrast, the extracellular cues that trigger these rearrangements in vivo are less well understood and are more diverse. Here, we review recent studies of the genetic regulation and cellular transitions involved in rosette formation. We discuss and compare specific models for rosette formation and highlight outstanding questions in the field.

Indexed as

Models, BiologicalAnimalsBody PatterningCell AdhesionCytoskeletonDrosophila melanogasterEpithelial CellsHumansKidney TubulesLateral Line SystemMorphogenesisNeural TubePancreasPhotoreceptor Cells, InvertebrateXenopus laevisZebrafishDrosophila epitheliumMorphogenesisMyosin IIRosetteZebrafish lateral line

Identifiers

PMID24961796
PMCPMC4067956
OpenAlexW2160153035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.