ArticleBrain sciences2013
Altered intrinsic functional connectivity in language-related brain regions in association with verbal memory performance in euthymic bipolar patients.
Article in Brain sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Large-scale network dysfunction in the acute state compared to the remitted state of bipolar disorder: A meta-analysis of resting-state functional connectivity.EBioMedicine · 2020Pooled it
- Resting-state functional connectivity in individuals with bipolar disorder during clinical remission: a systematic review.Journal of psychiatry & neuroscience : JPN · 2018Pooled it
- Structural and functional neural substrates underlying the concreteness effect.Brain structure & function · 2023Article
- Clinical neuropsychological characteristics of bipolar disorder, with a focus on cognitive and linguistic pattern: a conceptual analysis.F1000Research · 2023Review
- Discourse abilities in euthymic elderly patients with bipolar disorder: a preliminary study.Dementia & neuropsychologia · 2023Article
- The neural foundation of associative memory: a dynamic functional connectivity study for right-handed young adults.Experimental brain research · 2021Article
- Time-Frequency Characterization of Resting Brain in Bipolar Disorder during Euthymia-A Preliminary Study.Brain sciences · 2021Article
- Electroencephalographic Microstates in Schizophrenia and Bipolar Disorder.Frontiers in psychiatry · 2021Article
- Genetic Intersections of Language and Neuropsychiatric Conditions.Current psychiatry reports · 2020Review
- Altered Electroencephalographic Resting-State Large-Scale Brain Network Dynamics in Euthymic Bipolar Disorder Patients.Frontiers in psychiatry · 2019Article
- Abnormal intrinsic cerebro-cerebellar functional connectivity in un-medicated patients with bipolar disorder and major depressive disorder.Psychopharmacology · 2018Article
- Neurobiological Evidence for the Primacy of Mania Hypothesis.Current neuropharmacology · 2017Review
- Alterations of Intrinsic Brain Connectivity Patterns in Depression and Bipolar Disorders: A Critical Assessment of Magnetoencephalography-Based Evidence.Frontiers in psychiatry · 2017Review
- Differentiating unipolar and bipolar depression by alterations in large-scale brain networks.Human brain mapping · 2016Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Potential abnormalities in the structure and function of the temporal lobes have been studied much less in bipolar disorder than in schizophrenia. This may not be justified because language-related symptoms, such as pressured speech and flight of ideas, and cognitive deficits in the domain of verbal memory are amongst the hallmark of bipolar disorder (BD), and contribution of temporal lobe dysfunction is therefore likely. In the current study, we examined resting-state functional connectivity (FC) between the auditory cortex (Heschl's gyrus [HG], planum temporale [PT]) and whole brain using seed correlation analysis in n = 21 BD euthymic patients and n = 20 matched healthy controls and associated it with verbal memory performance. In comparison to controls BD patients showed decreased functional connectivity between Heschl's gyrus and planum temporale and the left superior and middle temporal gyrus. Additionally, fronto-temporal functional connectivity with the right inferior frontal/precentral gyrus and the insula was increased in patients. Verbal episodic memory deficits in the investigated sample of BD patients and language-related symptoms might therefore be associated with a diminished FC within the auditory/temporal gyrus and a compensatory fronto-temporal pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.