ArticleMolecular ecology resources2015
Genome assembly and annotation of a Drosophila simulans strain from Madagascar.
Article in Molecular ecology resources, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- The impact of P-element-induced hybrid dysgenesis on the male germline in Drosophila simulans.Genetics · 2026Article
- Haplotype structure: an overlooked key factor shaping the genomic selection response.Genetics · 2026Article
- Evolutionary Divergence of mTOR-mediated Transcriptional Regulation BetweenbioRxiv : the preprint server for biology · 2026Article
- Reduced Parallel Gene Expression Evolution With Increasing Genetic Divergence-A Hallmark of Polygenic Adaptation.Molecular ecology · 2025Article
- Effects of larval crowding on the transcriptome ofEvolutionary applications · 2023Article
- The genomic distribution of transposable elements is driven by spatially variable purifying selection.Nucleic acids research · 2023Article
- The Transposition Rate Has Little Influence on the Plateauing Level of the P-element.Molecular biology and evolution · 2022Article
- Natural variation in Drosophila shows weak pleiotropic effects.Genome biology · 2022Article
- Pool-GWAS on reproductive dormancy in Drosophila simulans suggests a polygenic architecture.G3 (Bethesda, Md.) · 2022Article
- The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime.Genome biology · 2021Article
- The Evolution of Phenotypic Plasticity in Response to Temperature Stress.Genome biology and evolution · 2020Article
- Fitness effects for Ace insecticide resistance mutations are determined by ambient temperature.BMC biology · 2020Article
- Article
- A Deep Learning Approach for Detecting Copy Number Variation in Next-Generation Sequencing Data.G3 (Bethesda, Md.) · 2019Article
- RaGOO: fast and accurate reference-guided scaffolding of draft genomes.Genome biology · 2019Article
- DNA Motifs Are Not General Predictors of Recombination in Two Drosophila Sister Species.Genome biology and evolution · 2019Article
- Genetic redundancy fuels polygenic adaptation in Drosophila.PLoS biology · 2019Article
- Article
- A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila.Genome biology · 2018Article
- Molecular dissection of a natural transposable element invasion.Genome research · 2018Article
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4 authors.
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Abstract
Drosophila simulans is a close relative of the genetic model D. melanogaster. Its worldwide distribution in combination with the absence of segregating chromosomal inversions makes this species an increasingly attractive model to study the molecular signatures of adaptation in natural and experimental populations. In an effort to improve the genomic resources for D. simulans, we assembled and annotated the genome of a strain originating from Madagascar (M252), the ancestral range of D. simulans. The comparison of the M252 genome to other available D. simulans assemblies confirmed its high quality, but also highlighted genomic regions that are difficult to assemble with NGS data. The annotation of M252 provides a clear improvement with alternative splicing for 52% of the multiple-exon genes, UTRs for 70% of the genes, 225 novel genes and 781 pseudogenes being reported. We anticipate that the M252 genome will be a valuable resource for many research questions.
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