ArticleBrain sciences2012
Physical activity, cognitive function, and brain health: what is the role of exercise training in the prevention of dementia?
Article in Brain sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of different physical activity interventions on executive function in older adults with dementia: a systematic review and network meta-analysis.Frontiers in neurology · 2025Pooled it
- Exercise interventions preserve hippocampal volume: A meta-analysis.Hippocampus · 2021Pooled it
- Pain-Reducing Effects of Physical Therapist-Delivered Interventions: A Systematic Review of Randomized Trials Among Older Adults With Dementia.Journal of geriatric physical therapy (2001)Pooled it
- Feasibility and preliminary efficacy of different intensities of functional training in elderly type 2 diabetes patients with cognitive impairment: a pilot randomised controlled trial.BMC geriatrics · 2024Trial
- Aerobic Exercise with Mediterranean-DASH Intervention for Neurodegenerative Delay Diet Promotes Brain Cells' Longevity despite Sex Hormone Deficiency in Postmenopausal Women: A Randomized Controlled Trial.Oxidative medicine and cellular longevity · 2022Trial
- The effect of the Mediterranean diet combined with physical activity on cognitive function in older adults: a scoping review.Journal of the International Society of Sports Nutrition · 2026Article
- Sex Differences in the Association Between Physical Functioning and Cognition in Two Central European Populations.European journal of neurology · 2025Article
- The long-term mental health benefits of exercise training for physical education students: a comprehensive review of neurobiological, psychological, and social effects.Frontiers in psychiatry · 2025Review
- The moderating role of walking in the association between HDL cholesterol and cognitive function among Korean older adults: a nationwide population-based cross-sectional study.Frontiers in public health · 2025Article
- Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals.Journal of Alzheimer's disease : JAD · 2024Article
- The role of physical activity in the physiological activation of the scholastic pre-requirements.AIMS neuroscience · 2024Article
- Going for gold: Sports and exercise groups for people with dementia and carers contribute to their well-being.Frontiers in rehabilitation sciences · 2022Article
- Cognitive and physical benefits of a game-like dual-task exercise among the oldest nursing home residents in Japan.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Daily-Life Physical Activity of Healthy Young Adults Associates With Function and Structure of the Hippocampus.Frontiers in human neuroscience · 2022Article
- Exercise Dosage in Reducing the Risk of Dementia Development: Mode, Duration, and Intensity-A Narrative Review.International journal of environmental research and public health · 2021Review
- Physical Activity and Cognitive Function in African American Older Adults Living With HIV.Journal of gerontological nursing · 2021Article
- Increased dynamic flexibility in the medial temporal lobe network following an exercise intervention mediates generalization of prior learning.Neurobiology of learning and memory · 2021Article
- Interventions to Preserve Cognitive Functioning Among Older Kidney Transplant Recipients.Current transplantation reports · 2020Article
- Article
- Serum Levels of BDNF in Cardiovascular Protection and in Response to Exercise.Arquivos brasileiros de cardiologia · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tor preventive measures are necessary to attenuate the increased economic and social burden of dementia. This review will focus on the potential for physical activity and exercise training to promote brain health and improve cognitive function via neurophysiological changes. We will review pertinent animal and human research examining the effects of physical activity on cognitive function and neurophysiology. We will discuss cross-sectional and longitudinal studies addressing the relationship between neurocognitive health and cardiorespiratory fitness or habitual activity level. We will then present and discuss longitudinal investigations examining the effects of exercise training on cognitive function and neurophysiology. We will conclude by summarizing our current understanding of the relationship between physical activity and brain health, and present areas for future research given the current gaps in our understanding of this issue.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.