Evidence map›Paper›PMID 24960690›Full record

ArticleDevelopmental cell2014

Copper homeostasis: specialized functions of the late secretory pathway.

Jonathan D Gitlin

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Wilson's disease: a comprehensive review of the molecular mechanisms.International journal of molecular sciences · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Jonathan D GitlinMarine Biological Laboratory, Woods Hole, MA 02543, USA. Electronic address: jgitlin@mbl.edu.

Funding

BIOLOGICAL ROLES OF COPPER IN HUMAN NUTRITIONR01DK044464 · NIDDK · WASHINGTON UNIVERSITY · PI GITLIN, JONATHAN DAVID · 1992 to 2004
$1.5M
NIDDK NIH HHS R01 DK044464
6 · The paper itself

Abstract

Differentiated cells have evolved mechanisms to adapt the functions of the late secretory pathway to the specific needs of the organism. Reporting in this issue of Developmental Cell, Polishchuk et al. (2014) demonstrate that hepatocytes utilize a unique exocytic aspect of the late endosomal/lysosomal compartment to maintain organismal copper homeostasis.

Indexed as

Adenosine TriphosphatasesAnimalsCation Transport ProteinsCopperCopper-Transporting ATPasesExocytosisGolgi ApparatusHomeostasisHumansLysosomesMaleAdenosine TriphosphatasesCation Transport ProteinsCopperCopper-Transporting ATPases

Identifiers

PMID24960690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.