ArticleIEEE transactions on medical imaging2014
Sparse matrix beamforming and image reconstruction for 2-D HIFU monitoring using harmonic motion imaging for focused ultrasound (HMIFU) with in vitro validation.
Article in IEEE transactions on medical imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Ultrasound Imaging: A Cornerstone of the Entire High-Intensity Focused Ultrasound Tumor Treatment Continuum.Diagnostics (Basel, Switzerland) · 2026Review
- Amplitude-Modulation Frequency Optimization for Enhancing Harmonic Motion Imaging Performance of Breast Tumors in the Clinic.Ultrasound in medicine & biology · 2025Article
- Three-Dimensional Super-Resolution Passive Cavitation Mapping in Laser Lithotripsy.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Article
- Optimization of the Tracking Beam Sequence in Harmonic Motion Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Article
- An analytical model of full-field displacement and strain induced by amplitude-modulated focused ultrasound in harmonic motion imaging.Physics in medicine and biology · 2021Article
- Real-Time Passive Acoustic Mapping Using Sparse Matrix Multiplication.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Harmonic Motion Imaging of Pancreatic Tumor Stiffness Indicates Disease State and Treatment Response.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020Article
- Article
- Technical Note: In vivo Young's modulus mapping of pancreatic ductal adenocarcinoma during HIFU ablation using harmonic motion elastography (HME).Medical physics · 2018Article
- Fast lesion mapping during HIFU treatment using harmonic motion imaging guided focused ultrasound (HMIgFUS) in vitro and in vivo.Physics in medicine and biology · 2017Article
- Mechanics of ultrasound elastography.Proceedings. Mathematical, physical, and engineering sciences · 2017Review
- 3D Quasi-Static Ultrasound Elastography With Plane Wave In Vivo.IEEE transactions on medical imaging · 2017Article
- Elasticity mapping of murine abdominal organs in vivo using harmonic motion imaging (HMI).Physics in medicine and biology · 2016Article
- Tumor characterization and treatment monitoring of postsurgical human breast specimens using harmonic motion imaging (HMI).Breast cancer research : BCR · 2016Article
- Real-time Monitoring of High Intensity Focused Ultrasound (HIFU) Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound (HMIFU).Journal of visualized experiments : JoVE · 2015Article
- Harmonic motion imaging for abdominal tumor detection and high-intensity focused ultrasound ablation monitoring: an in vivo feasibility study in a transgenic mouse model of pancreatic cancer.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2015Article
- High intensity focused ultrasound (HIFU) focal spot localization using harmonic motion imaging (HMI).Physics in medicine and biology · 2015Article
- High-intensity focused ultrasound monitoring using harmonic motion imaging for focused ultrasound (HMIFU) under boiling or slow denaturation conditions.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2015Article
- Thermometry and ablation monitoring with ultrasound.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2015Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Harmonic motion imaging for focused ultrasound (HMIFU) utilizes an amplitude-modulated HIFU beam to induce a localized focal oscillatory motion simultaneously estimated. The objective of this study is to develop and show the feasibility of a novel fast beamforming algorithm for image reconstruction using GPU-based sparse-matrix operation with real-time feedback. In this study, the algorithm was implemented onto a fully integrated, clinically relevant HMIFU system. A single divergent transmit beam was used while fast beamforming was implemented using a GPU-based delay-and-sum method and a sparse-matrix operation. Axial HMI displacements were then estimated from the RF signals using a 1-D normalized cross-correlation method and streamed to a graphic user interface with frame rates up to 15 Hz, a 100-fold increase compared to conventional CPU-based processing. The real-time feedback rate does not require interrupting the HIFU treatment. Results in phantom experiments showed reproducible HMI images and monitoring of 22 in vitro HIFU treatments using the new 2-D system demonstrated reproducible displacement imaging, and monitoring of 22 in vitro HIFU treatments using the new 2-D system showed a consistent average focal displacement decrease of 46.7 ±14.6% during lesion formation. Complementary focal temperature monitoring also indicated an average rate of displacement increase and decrease with focal temperature at 0.84±1.15%/(°)C, and 2.03±0.93%/(°)C , respectively. These results reinforce the HMIFU capability of estimating and monitoring stiffness related changes in real time. Current ongoing studies include clinical translation of the presented system for monitoring of HIFU treatment for breast and pancreatic tumor applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.