ArticlePloS one2014
Transcriptomic analysis of Prunus domestica undergoing hypersensitive response to plum pox virus infection.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The Effect of Viral Infection on the Growth of HoneySweet GM Plum Trees.Plants (Basel, Switzerland) · 2026Article
- Article
- The Mechanism of Resistance of EUROPEAN Plum toPlants (Basel, Switzerland) · 2023Article
- DecipheringMetabolites · 2021Review
- Abscisic Acid Connects Phytohormone Signaling with RNA Metabolic Pathways and Promotes an Antiviral Response that Is Evaded by a Self-Controlled RNA Virus.Plant communications · 2020Article
- Resistance to Plum Pox Virus (PPV) in apricot (Prunus armeniaca L.) is associated with down-regulation of two MATHd genes.BMC plant biology · 2018Article
- Coexpression network analysis of the genes regulated by two types of resistance responses to powdery mildew in wheat.Scientific reports · 2016Article
- Identification of Candidate Anthocyanin-Related Genes by Transcriptomic Analysis of 'Furongli' Plum (Prunus salicina Lindl.) during Fruit Ripening Using RNA-Seq.Frontiers in plant science · 2016Article
- Omics studies of citrus, grape and rosaceae fruit trees.Breeding science · 2016Review
- Application of Genomic Technologies to the Breeding of Trees.Frontiers in genetics · 2016Review
- De novo transcriptome assembly of two different Prunus salicina cultivars.Genomics data · 2015Article
- RNA polymerase slippage as a mechanism for the production of frameshift gene products in plant viruses of the potyviridae family.Journal of virology · 2015Article
- Gene Expression Analysis of Plum pox virus (Sharka) Susceptibility/Resistance in Apricot (Prunus armeniaca L.).PloS one · 2015Article
- Prunus transcription factors: breeding perspectives.Frontiers in plant science · 2015Review
- Biotechnological strategies and tools for Plum pox virus resistance: trans-, intra-, cis-genesis, and beyond.Frontiers in plant science · 2015Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plum pox virus (PPV) infects Prunus trees around the globe, posing serious fruit production problems and causing severe economic losses. One variety of Prunus domestica, named 'Jojo', develops a hypersensitive response to viral infection. Here we compared infected and non-infected samples using next-generation RNA sequencing to characterize the genetic complexity of the viral population in infected samples and to identify genes involved in development of the resistance response. Analysis of viral reads from the infected samples allowed reconstruction of a PPV-D consensus sequence. De novo reconstruction showed a second viral isolate of the PPV-Rec strain. RNA-seq analysis of PPV-infected 'Jojo' trees identified 2,234 and 786 unigenes that were significantly up- or downregulated, respectively (false discovery rate; FDR≤0.01). Expression of genes associated with defense was generally enhanced, while expression of those related to photosynthesis was repressed. Of the total of 3,020 differentially expressed unigenes, 154 were characterized as potential resistance genes, 10 of which were included in the NBS-LRR type. Given their possible role in plant defense, we selected 75 additional unigenes as candidates for further study. The combination of next-generation sequencing and a Prunus variety that develops a hypersensitive response to PPV infection provided an opportunity to study the factors involved in this plant defense mechanism. Transcriptomic analysis presented an overview of the changes that occur during PPV infection as a whole, and identified candidates suitable for further functional characterization.
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