Evidence map›Paper›PMID 24959701›Full record

SynthesisEmerging infectious diseases2014

Epidemiology, clinical manifestations, and outcomes of Streptococcus suis infection in humans.

Vu Thi Lan Huong, Ngo Ha, Nguyen Tien Huy, Peter Horby, Ho Dang Trung Nghia, Vu Dinh Thiem, Xiaotong Zhu, Ngo Thi Hoa, Tran Tinh Hien, Javier Zamora and 3 more

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Emerging infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 6 pooled it
18.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 6 syntheses or guidelines pooled it, 280 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Identification ofVirulence · 2021
    Pooled it
  4. Pooled it
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  7. Trial
  8. Article
  9. Review
  10. Article
  11. The cholesterol-dependent cytolysin promotesInfection and immunity · 2026
    Article
  12. Review
  13. Article
  14. Article
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  17. Pyogenic Spondylitis with Epidural Abscess Caused byPathogens (Basel, Switzerland) · 2026
    Article
  18. Article
  19. Article
  20. Review

105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 5 countries.

Vu Thi Lan Huong
Ngo Ha
Nguyen Tien Huy
Peter Horby
Ho Dang Trung Nghia
Vu Dinh Thiem
Xiaotong Zhu
Ngo Thi Hoa
Tran Tinh Hien
Javier Zamora
Constance Schultsz
Heiman Frank Louis Wertheim
Kenji Hirayama
Oxford University Clinical Research Unit · VNUniversity of Oxford · GBCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESUniversity of Amsterdam · NL

Funding

Wellcome Trust
6 · The paper itself

Abstract

Streptococcus suis, a bacterium that affects pigs, is a neglected pathogen that causes systemic disease in humans. We conducted a systematic review and meta-analysis to summarize global estimates of the epidemiology, clinical characteristics, and outcomes of this zoonosis. We searched main literature databases for all studies through December 2012 using the search term "streptococcus suis." The prevalence of S. suis infection is highest in Asia; the primary risk factors are occupational exposure and eating of contaminated food. The pooled proportions of case-patients with pig-related occupations and history of eating high-risk food were 38.1% and 37.3%, respectively. The main clinical syndrome was meningitis (pooled rate 68.0%), followed by sepsis, arthritis, endocarditis, and endophthalmitis. The pooled case-fatality rate was 12.8%. Sequelae included hearing loss (39.1%) and vestibular dysfunction (22.7%). Our analysis identified gaps in the literature, particularly in assessing risk factors and sequelae of this infection.

Indexed as

AdultAnimalsCase-Control StudiesCommunicable DiseasesCross-Sectional StudiesFemaleHumansMaleMiddle AgedOccupationsRisk FactorsStreptococcal InfectionsStreptococcus suisSus scrofaSwineZoonosesbacteriabacterial meningitishumansmeta-analysisStreptococcus suissystematic reviewzoonoses

Identifiers

PMID24959701
PMCPMC4073838
OpenAlexW2076971528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.