Evidence map›Paper›PMID 24959505›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Role of serum ß-carotene in the diagnosis and prevention of oral squamous cell carcinoma - a case control study.

Prashanthi Chippagiri, Ali Im, Spoorthi Ravi Banavar

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Prashanthi ChippagiriSenior Lecturer, Department of Oral Medicine, M.S.Ramaiah Dental College and Hospital , Bangalore, Karnataka, India .
Ali ImProfessor, Department of Oral Medicine, College of Dental Sciences , Davangere, Karnataka, India .
Spoorthi Ravi BanavarReader, Department of Oral Pathology, M.S.Ramaiah Dental College and Hospital , Bangalore, Karnataka, India .
KIIT University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextOral squamous cell carcinoma (OSCC) is the most common cancer of the head and neck. It accounts for more than 90% of all malignancies Which occur in the head and neck region. The high incidence and mortality rate of oral cancer stimulates continuation of research on finding new diagnostic tools or markers for it.

aimTo evaluate the possible role of serum β-carotene as a biochemical parameter in the diagnosis of oral squamous cell carcinoma. MATERIALS AND

methodsThe serumβ-carotene levels in 40 patients with clinically diagnosed and histopathologically confirmed oral squamous cell carcinoma were estimated and the levels were compared with those of 40 healthy controls. The serum β-carotene levels were estimated by using a spectrophotometer. The data which was obtained was analyzed statistically by using unpaired t-test.

resultsSubjects with oral squamous cell carcinoma showed significantly lower levels of mean serum β-carotene (149.95 ± 61.29) as compared to those seen in controls (278.19 ± 90.12).

conclusionThe results of the present study are encouraging and they suggest that the estimation of the low levels of β-carotene in the patients with oral squamous cell carcinoma may be a useful diagnostic tool for making the diagnosis of oral squamous Cell carcinoma and thereby improving the prognosis of this dreaded disease.

Indexed as

Biochemical markerOral squamous cell carcinomaSerum β-carotene levels

Identifiers

PMID24959505
PMCPMC4064902
OpenAlexW2044537413

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.