Evidence map›Paper›PMID 24959214›Full record

ArticleOncology letters2014

Genetic alterations of chromosomes, p53 and p16 genes in low- and high-grade bladder cancer.

Deniz Abat, Osman Demirhan, Nihal Inandiklioglu, Erdal Tunc, Seyda Erdogan, Deniz Tastemir, Inayet Nur Uslu, Zuhtu Tansug

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Role of SWI/SNF Complex in Bladder Cancer.Journal of cellular and molecular medicine · 2025
    Review
  4. The relationship between P16Scientific reports · 2022
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Deniz AbatDepartment of Urology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Osman DemirhanDepartment of Medical Biology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Nihal InandikliogluDepartment of Medical Biology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Erdal TuncDepartment of Medical Biology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Seyda ErdoganDepartment of Pathology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Deniz TastemirVocational School of Health Services, Adıyaman University, 02040 Adıyaman, Turkey.
Inayet Nur UsluDepartment of Medical Biology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Zuhtu TansugDepartment of Urology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
Cukurova University · TRAdıyaman University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A majority of patients with bladder cancer present with superficial disease and subsequently, some patients show progression to muscle invasive or metastatic disease. Bladder cancer has a complex genetic process and identification of the genetic alterations which occur during progression may lead to the understanding of the nature of the disease and provide the possibility of early treatment. The aim of the present study was to compare the structural and numerical chromosomal differences and changes in the p16 and p53 genes between low-grade (LG) and high-grade (HG) bladder cancer (BC) using cytogenetic and molecular cytogenetic methods. Between March 2009 and March 2010, cytogenetic analyses were carried out on tumor and blood samples in 34 patients with transitional cell type BC, and on blood samples of 34 healthy patients as a control group. Fluorescence

Indexed as

bladder carcinomachromosomal aberrationsfluorescence in situ hybridizationhigh gradelow gradep16p53

Identifiers

PMID24959214
PMCPMC4063627
OpenAlexW2002033794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.