ArticleOncology letters2014
Histological and molecular aspects of oral squamous cell carcinoma (Review).
Article in Oncology letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
111 citing papers in PubMed, 2 syntheses or guidelines pooled it, 258 citations in OpenAlex.
- Emerging histopathologic markers in early-stage oral tongue cancer: A systematic review and meta-analysis.Head & neck · 2022Pooled it
- High-throughput nucleotide sequencing for bacteriome studies in oral squamous cell carcinoma: a systematic review.Oral and maxillofacial surgery · 2020Pooled it
- Identification of potential biomarkers for oral squamous cell carcinoma through multi-cohort bioinformatic analysis.Journal of the Egyptian National Cancer Institute · 2026Article
- Chronic Osteomyelitis or Squamous Cell Carcinoma of the Mandible: A Case Report With Diagnostic Challenges.Cureus · 2026Article
- Exploring lived experiences in oral cavity cancer: an Asia-Pacific perspective on psychosocial challenges and opportunities for enhanced patient-centric care.Journal of cancer survivorship : research and practice · 2026Article
- Impact of Zirconia and Titanium Implant Surfaces of Different Roughness on Oral Epithelial Cells.Dentistry journal · 2026Article
- Low ALDH1A1 expression in relation to nodal metastasis and survival in tongue squamous cell carcinoma.PloS one · 2026Article
- Immunohistochemical expression of epithelial mesenchymal transition proteins ZEB1 and E-cadherin in oral leukoplakia and oral squamous cell carcinoma.World journal of experimental medicine · 2025Article
- Article
- Methylation-Driven downregulation of GABRB2 in oral carcinoma's subtype: implications for early diagnosis and differentiation.BMC oral health · 2025Article
- Dental implant-associated oral squamous cell carcinoma: a clinical retrospective study of 22 cases.Maxillofacial plastic and reconstructive surgery · 2025Article
- Plasma cytokine profiles in oral and oropharyngeal squamous cell carcinoma.BMC oral health · 2025Article
- Article
- Choline transporter-like protein 1 in tongue squamous cell carcinoma: implications for cell proliferation and differentiation.Scientific reports · 2025Article
- Vitamin DInternational journal of molecular sciences · 2025Article
- Perspectives on the Application of Biosensors for the Early Detection of Oral Cancer.Sensors (Basel, Switzerland) · 2025Review
- Therapeutic effects of quercetin in oral cancer therapy: a systematic review of preclinical evidence focused on oxidative damage, apoptosis and anti-metastasis.Cancer cell international · 2025Review
- Review
- Unveiling Oral Cancer Epidemiology in Pakistan: Insights From a Case-Control Study.Global health, epidemiology and genomics · 2025Article
- gamUnet: designing global attention-based CNN architectures for enhanced oral cancer detection and segmentation.Frontiers in medicine · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral squamous cell carcinoma (OSCC) represents 95% of all forms of head and neck cancer, and over the last decade its incidence has increased by 50%. Oral carcinogenesis is a multistage process, which simultaneously involves precancerous lesions, invasion and metastasis. Degradation of the cell cycle and the proliferation of malignant cells results in the loss of control mechanisms that ensure the normal function of tissues. The aim of the current review is to present the histopathological features of OSCC, including potentially malignant changes, the international classification of tumors, the tumor invasion front and tumor biomarkers (Ki-67, p53, homeobox genes and collagen type IV), as well as the tumor microenvironment and function of cancer-associated fibroblasts in the most common type of oral cancer that is encountered by dental surgeons. In OSCC, associations have been identified between the proliferation, basal lamina degradation and connective tissue modulation. Therefore, the comparison of these factors with the survival time of OSCC patients from the histopathological diagnosis is of interest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.