ArticleProceedings of the National Academy of Sciences of the United States of America2014
Extensive sampling of basidiomycete genomes demonstrates inadequacy of the white-rot/brown-rot paradigm for wood decay fungi.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 303 papers.
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Who cites it
303 citing papers in PubMed, 742 citations in OpenAlex.
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- Improved chromosome-level genome assembly of Pleurotus ostreatus CCMSSC 00389.G3 (Bethesda, Md.) · 2026Article
- The "dark magic mushroom" co-produces amatoxins and psilocybin.bioRxiv : the preprint server for biology · 2026Article
- Reintroduction of lignin-modifying enzymes in the brown-rot fungus Gloeophyllum trabeum restores ligninolytic activities but diminishes lignocellulose degradation.Fungal biology and biotechnology · 2026Article
- Genomic and Metabolomic Comparisons Provide New Insights into Plant Cell Wall Degradation, Mating Diversity and Secondary Metabolites in Brown and White CommercialInternational journal of molecular sciences · 2026Article
- Pan-genome based on chromosome sequences of wild and cultivated Agaricus bisporus.Scientific data · 2026Article
- Molecular biology of Pleurotus mushrooms: genomic resources, genetic manipulation, and regulation mechanisms.Antonie van Leeuwenhoek · 2026Review
- Urbanization increases the complexity of soil microbial interaction networks.Communications biology · 2026Article
- Establishment of a congenic strain for the oyster mushroom reveals the structure and evolution of mating-type loci.PLoS genetics · 2026Article
- Temporal Variation in Mechanical and Chemical Properties of Bamboo Decayed byJournal of fungi (Basel, Switzerland) · 2026Article
- Elevated graminoid cover co-occurs with Ascomycota-dominated soils in Longyearbyen, Svalbard.FEMS microbiology ecology · 2026Article
- Gene duplication, horizontal gene transfer, and trait trade-offs drive evolution of postfire resource acquisition in pyrophilous fungi.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genome Sequences of Three Polyporaceae Species (Polyporales, Basidiomycota) from South Korea.Mycobiology · 2026Article
- Immunolocalization of matrix polysaccharides during wood decay by white rot fungus: evidence for specific interaction between hemicellulose and lignin in the wood fibre cell wall ofFrontiers in plant science · 2026Article
243 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
25 authors at 11 institutions in 3 countries.
Funding
Abstract
Basidiomycota (basidiomycetes) make up 32% of the described fungi and include most wood-decaying species, as well as pathogens and mutualistic symbionts. Wood-decaying basidiomycetes have typically been classified as either white rot or brown rot, based on the ability (in white rot only) to degrade lignin along with cellulose and hemicellulose. Prior genomic comparisons suggested that the two decay modes can be distinguished based on the presence or absence of ligninolytic class II peroxidases (PODs), as well as the abundance of enzymes acting directly on crystalline cellulose (reduced in brown rot). To assess the generality of the white-rot/brown-rot classification paradigm, we compared the genomes of 33 basidiomycetes, including four newly sequenced wood decayers, and performed phylogenetically informed principal-components analysis (PCA) of a broad range of gene families encoding plant biomass-degrading enzymes. The newly sequenced Botryobasidium botryosum and Jaapia argillacea genomes lack PODs but possess diverse enzymes acting on crystalline cellulose, and they group close to the model white-rot species Phanerochaete chrysosporium in the PCA. Furthermore, laboratory assays showed that both B. botryosum and J. argillacea can degrade all polymeric components of woody plant cell walls, a characteristic of white rot. We also found expansions in reducing polyketide synthase genes specific to the brown-rot fungi. Our results suggest a continuum rather than a dichotomy between the white-rot and brown-rot modes of wood decay. A more nuanced categorization of rot types is needed, based on an improved understanding of the genomics and biochemistry of wood decay.
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