ArticleProceedings of the National Academy of Sciences of the United States of America2014
Contact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strains.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Darwin review: the evolution of virulence in human pathogens.Proceedings. Biological sciences · 2024Review
- Ecological and evolutionary dynamics of multi-strain RNA viruses.Nature ecology & evolution · 2022Review
- Asymmetric host movement reshapes local disease dynamics in metapopulations.Scientific reports · 2022Article
- A threat from both sides: Multiple introductions of genetically distinct H5 HPAI viruses into Canada via both East Asia-Australasia/Pacific and Atlantic flyways.Virus evolution · 2022Article
- Review
- Parallel evolution in the emergence of highly pathogenic avian influenza A viruses.Nature communications · 2020Article
- Avian influenza viruses at the wild-domestic bird interface in Egypt.Infection ecology & epidemiology · 2019Review
- Evolution of Copy Number at the MHC Varies across the Avian Tree of Life.Genome biology and evolution · 2019Article
- Article
- Antibody responses to avian influenza viruses in wild birds broaden with age.Proceedings. Biological sciences · 2016Article
- MANTIS: an R package that simulates multilocus models of pathogen evolution.BMC bioinformatics · 2015Article
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3 authors.
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Abstract
Outbreaks of highly pathogenic strains of avian influenza viruses (AIVs) cause considerable economic losses to the poultry industry and also pose a threat to human life. The possibility that one of these strains will evolve to become transmissible between humans, sparking a major influenza pandemic, is a matter of great concern. Most studies so far have focused on assessing these odds from the perspective of the intrinsic mutability of AIV rather than the ecological constraints to invasion faced by the virus population. Here we present an alternative multihost model for the evolution of AIV in which the mode and tempo of mutation play a limited role, with the emergence of strains being determined instead principally by the prevailing profile of population-level immunity. We show that (i) many of the observed differences in influenza virus dynamics among species can be captured by our model by simply varying host lifespan and (ii) increased contact between species of different lifespans can promote the emergence of potentially more virulent strains that were hitherto suppressed in one of the species.
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