Evidence map›Paper›PMID 24958641›Full record

ArticleDiagnostic microbiology and infectious disease2014

Dual-site sampling improved detection rates for MRSA colonization in patients with cutaneous abscesses.

L May, C McCann, G Brooks, R Rothman, L Miller, J Jordan

Open access · greenAbstract read
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

L MayDepartment of Emergency Medicine, The George Washington University Medical Faculty Associates, Washington, DC; Department of Epidemiology and Biostatistics, School of Public Health and Health Services, The George Washington University, Washington, DC. Electronic address: larissa@gwu.edu.
C McCannDepartment of Epidemiology and Biostatistics, School of Public Health and Health Services, The George Washington University, Washington, DC.
G BrooksDepartment of Emergency Medicine, The George Washington University Medical Faculty Associates, Washington, DC; Department of Epidemiology and Biostatistics, School of Public Health and Health Services, The George Washington University, Washington, DC.
R RothmanDepartment of Emergency Medicine, Johns Hopkins University, Baltimore, MD.
L MillerInfectious Disease Clinical Outcomes Research Unit, Division of Infectious Disease, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA.
J JordanDepartment of Epidemiology and Biostatistics, School of Public Health and Health Services, The George Washington University, Washington, DC.
George Washington University · USJohns Hopkins University · USThe Lundquist Institute · USWashington University Medical Center · US

Funding

Clinical and Translational Science Institute at Children's NationalUL1TR000075 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2012 to 2015
$13.7M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031988 · NCRR · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2010 to 2011
$8.2M
Clinical and Translational Science Institute at Children's NationalKL2TR000076 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2012 to 2014
$756k
Clinical and Translational Science Institute at Children's NationalKL2RR031987 · NCRR · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2010 to 2011
$425k
NCATS NIH HHS KL2 TR000076NCATS NIH HHS KL2TR000076NCATS NIH HHS UL1 TR000075NCATS NIH HHS UL1TR000075NCRR NIH HHS KL2 RR031987NCRR NIH HHS KL2RR031987NCRR NIH HHS UL1 RR031988NCRR NIH HHS UL1RR031988NIAID NIH HHS L30 AI107906
6 · The paper itself

Abstract

Extranasal sites are common reservoirs of Staphylococcus aureus colonization and may be relevant for methicillin-resistant S. aureus (MRSA) screening and infection control strategies. The objective here was to determine whether inguinal specimens could also be screened using Xpert SA Nasal Complete assay for MRSA. Results were compared to broth enrichment culture. Among 162 consented adults seeking care in the emergency department for cutaneous abscesses, inguinal specimens were found positive for MRSA more often than nares specimens, 24% and 26% by PCR or culture, respectively, compared to 19% each by PCR or culture. Overall, 6% of adults colonized with MRSA would have been missed by nares screening alone. Compared to culture, Xpert SA Nasal Complete assay demonstrated sensitivity and specificity of 89% and 97%, respectively, for detecting nares and/or inguinal MRSA colonization. In conclusion, inguinal specimens were a more common reservoir for MRSA than nares specimens in this population of patients.

Indexed as

AbscessAdolescentAdultAgedAged, 80 and overBacteriological TechniquesCarrier StateFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedNasal CavityProspective StudiesSensitivity and SpecificityStaphylococcal InfectionsCutaneous abscessEmergency departmentInfection controlMolecular diagnostics

Identifiers

PMID24958641
PMCPMC4162831
OpenAlexW2068223539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.