Evidence map›Paper›PMID 24958588›Full record

ArticlePediatrics2014

Autism spectrum disorders and race, ethnicity, and nativity: a population-based study.

Tracy A Becerra, Ondine S von Ehrenstein, Julia E Heck, Jorn Olsen, Onyebuchi A Arah, Shafali S Jeste, Michael Rodriguez, Beate Ritz

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02786420 (Imaging Innovations for Placental Assessment in Response to Environmental Pollution), which is not on this map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02786420 completednot on this mapstarted 2015, after this paper: background citation

Imaging Innovations for Placental Assessment in Response to Environmental Pollution

TypeobservationalSponsorUniversity of California, Los AngelesRan2015 to 2020Enrolled199ConditionsPlacental Disease
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 179 citations in OpenAlex.

  1. Pooled it
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  15. Experiences of siblings of individuals with autism spectrum disorders.International journal of developmental disabilities · 2025
    Article
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  19. Unpacking the prevalence: A warning against overstating the recently narrowed gap for Black autistic youth.Autism research : official journal of the International Society for Autism Research · 2024
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tracy A BecerraDepartments of Epidemiology, and.
Ondine S von EhrensteinCommunity Health Sciences, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California; and.
Julia E HeckDepartments of Epidemiology, and.
Jorn OlsenDepartments of Epidemiology, and.
Onyebuchi A ArahDepartments of Epidemiology, and.
Shafali S JesteDepartments of Psychiatry and Behavioral Sciences, and.
Michael RodriguezFamily Medicine, University of California, Los Angeles, Los Angeles, California.
Beate RitzDepartments of Epidemiology, and britz@ucla.edu.
University of California, Los Angeles · USInstitute of Behavioral Sciences · JP

Funding

Statistics and Methods CoreR24HD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SELTZER, JUDITH A. · 2001 to 2016
$10.1M
Pesticide Exposure and Childhood AutismR21ES022389 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VON EHRENSTEIN, ONDINE · 2014 to 2015
$407k
NICHD NIH HHS R24 HD041022NICHD NIH HHS R24HD041022NIEHS NIH HHS R21 ES022389NIEHS NIH HHS R21ES022389
6 · The paper itself

Abstract

objectiveOur understanding of the influence of maternal race/ethnicity and nativity and childhood autistic disorder (AD) in African Americans/blacks, Asians, and Hispanics in the United States is limited. Phenotypic differences in the presentation of childhood AD in minority groups may indicate etiologic heterogeneity or different thresholds for diagnosis. We investigated whether the risk of developing AD and AD phenotypes differed according to maternal race/ethnicity and nativity.

methodsChildren born in Los Angeles County with a primary AD diagnosis at ages 3 to 5 years during 1998-2009 were identified and linked to 1995-2006 California birth certificates (7540 children with AD from a cohort of 1,626,354 births). We identified a subgroup of children with AD and a secondary diagnosis of mental retardation and investigated heterogeneity in language and behavior.

resultsWe found increased risks of being diagnosed with AD overall and specifically with comorbid mental retardation in children of foreign-born mothers who were black, Central/South American, Filipino, and Vietnamese, as well as among US-born Hispanic and African American/black mothers, compared with US-born whites. Children of US African American/black and foreign-born black, foreign-born Central/South American, and US-born Hispanic mothers were at higher risk of exhibiting an AD phenotype with both severe emotional outbursts and impaired expressive language than children of US-born whites.

conclusionsMaternal race/ethnicity and nativity are associated with offspring's AD diagnosis and severity. Future studies need to examine factors related to nativity and migration that may play a role in the etiology as well as identification and diagnosis of AD in children.

Indexed as

AsianBlack or African AmericanHispanic or LatinoWhite PeopleCaliforniaChild Development Disorders, PervasiveChild, PreschoolFemaleHumansMaleMothersRacial Groupsautistic disordercontinental population groupsemigration and immigrationepidemiology

Identifiers

PMID24958588
PMCPMC4067639
OpenAlexW2016905119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.