ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2014
The gene expression database for mouse development (GXD): putting developmental expression information at your fingertips.
Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The mouse Gene Expression Database (GXD): 2026 update.Nucleic acids research · 2026Article
- Mouse Genome Informatics: an integrated knowledgebase system for the laboratory mouse.Genetics · 2024Article
- Cell-based allometry: an approach for evaluation of complexity in morphogenesis.Quantitative biology (Beijing, China) · 2023Article
- Skeletal Muscle's Role in Prenatal Inter-organ Communication: A Phenogenomic Study with Qualitative Citation Analysis.Advances in anatomy, embryology, and cell biology · 2023Article
- The mouse Gene Expression Database (GXD): 2021 update.Nucleic acids research · 2021Article
- Evolving Role of RING1 and YY1 Binding Protein in the Regulation of Germ-Cell-Specific Transcription.Genes · 2019Review
- Developmental biology of the meninges.Genesis (New York, N.Y. : 2000) · 2019Review
- The mouse Gene Expression Database (GXD): 2019 update.Nucleic acids research · 2019Article
- The mouse Gene Expression Database (GXD): 2017 update.Nucleic acids research · 2017Article
- Searching the Mouse Genome Informatics (MGI) Resources for Information on Mouse Biology from Genotype to Phenotype.Current protocols in bioinformatics · 2016Article
- Representation of anatomy in online atlases and databases: a survey and collection of patterns for interface design.BMC developmental biology · 2016Article
- Characterization of the hypothalamic transcriptome in response to food deprivation reveals global changes in long noncoding RNA, and cell cycle response genes.Genes & nutrition · 2015Article
- GXD: a community resource of mouse Gene Expression Data.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Article
- The mouse gene expression database: New features and how to use them effectively.Genesis (New York, N.Y. : 2000) · 2015Article
- High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.Bone research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Because molecular mechanisms of development are extraordinarily complex, the understanding of these processes requires the integration of pertinent research data. Using the Gene Expression Database for Mouse Development (GXD) as an example, we illustrate the progress made toward this goal, and discuss relevant issues that apply to developmental databases and developmental research in general. Since its first release in 1998, GXD has served the scientific community by integrating multiple types of expression data from publications and electronic submissions and by making these data freely and widely available. Focusing on endogenous gene expression in wild-type and mutant mice and covering data from RNA in situ hybridization, in situ reporter (knock-in), immunohistochemistry, reverse transcriptase-polymerase chain reaction, Northern blot, and Western blot experiments, the database has grown tremendously over the years in terms of data content and search utilities. Currently, GXD includes over 1.4 million annotated expression results and over 260,000 images. All these data and images are readily accessible to many types of database searches. Here we describe the data and search tools of GXD; explain how to use the database most effectively; discuss how we acquire, curate, and integrate developmental expression information; and describe how the research community can help in this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.