ArticleThe American journal of tropical medicine and hygiene2014
Phylogeography of Rickettsia rickettsii genotypes associated with fatal Rocky Mountain spotted fever.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
- Spotted Fever Rickettsioses in Panama: New Cases and the Gaps That Hinder Its Epidemiological Understanding.Pathogens (Basel, Switzerland) · 2025Article
- Analysis of Rocky Mountain spotted fever cases in Northern Mexico reveals genetic variability of Rickettsia rickettsii and the different distribution of genotypes.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Evaluation of a mimotope of the Rickettsia outer membrane protein A (OmpA) as an antigen in enzyme-linked immunosorbent assay to detect rickettsiosis in capybaras (Hydrochoerus hydrochaeris), horses (Equus caballus), and opossums (Didelphis sp.).Experimental & applied acarology · 2023Article
- Nitric Oxide Inhibition of Rickettsia rickettsii.Infection and immunity · 2021Article
- Unpacking the intricacies of Rickettsia-vector interactions.Trends in parasitology · 2021Review
- Assessment of the Pathogenicity ofVector borne and zoonotic diseases (Larchmont, N.Y.) · 2021Article
- Isolate-Dependent Differences in Clinical, Pathological, and Transcriptional Profiles followingInfection and immunity · 2021Article
- Comparative Analysis of Infection byPathogens (Basel, Switzerland) · 2020Article
- Molecular Confirmation of Rocky Mountain Spotted Fever Epidemic Agent in Mexicali, Mexico.Emerging infectious diseases · 2018Article
- Diagnosis of Spotted Fever Group Rickettsioses in U.S. Travelers Returning from Africa, 2007-2016.The American journal of tropical medicine and hygiene · 2018Article
- Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan.Genome biology and evolution · 2017Article
- The Eco-epidemiology of Pacific Coast Tick Fever in California.PLoS neglected tropical diseases · 2016Article
- Phylogeography of Rhipicephalus sanguineus sensu lato and its relationships with climatic factors.Experimental & applied acarology · 2016Article
- Epidemiological surveillance of capybaras and ticks on warning area for Brazilian spotted fever.Veterinary world · 2015Article
- Comparative genome sequencing of Rickettsia rickettsii strains that differ in virulence.Infection and immunity · 2015Article
- Challenges posed by tick-borne rickettsiae: eco-epidemiology and public health implications.Frontiers in public health · 2015Review
- Genetic identification of rickettsial isolates from fatal cases of Brazilian spotted fever and comparison with Rickettsia rickettsii isolates from the American continents.Journal of clinical microbiology · 2014Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rocky Mountain spotted fever (RMSF), a tick-borne zoonosis caused by Rickettsia rickettsii, is among the deadliest of all infectious diseases. To identify the distribution of various genotypes of R. rickettsii associated with fatal RMSF, we applied molecular typing methods to samples of DNA extracted from formalin-fixed, paraffin-embedded tissue specimens obtained at autopsy from 103 case-patients from seven countries who died of RMSF. Complete sequences of one or more intergenic regions were amplified from tissues of 30 (29%) case-patients and revealed a distribution of genotypes consisting of four distinct clades, including the Hlp clade, regarded previously as a non-pathogenic strain of R. rickettsii. Distinct phylogeographic patterns were identified when composite case-patient and reference strain data were mapped to the state and country of origin. The phylogeography of R. rickettsii is likely determined by ecological and environmental factors that exist independently of the distribution of a particular tick vector.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.