ArticleMetabolites2014
Breath analysis in disease diagnosis: methodological considerations and applications.
Article in Metabolites, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 308 citations in OpenAlex.
- Medical diagnosis at the point-of-care by portable high-field asymmetric waveform ion mobility spectrometry: a systematic review and meta-analysis.Journal of breath research · 2021Pooled it
- A Study of Diagnostic Accuracy Using a Chemical Sensor Array and a Machine Learning Technique to Detect Lung Cancer.Sensors (Basel, Switzerland) · 2018Trial
- Rapid photoacoustic trace gas sensor for online end-tidal CO monitoring in exhaled breath.Photoacoustics · 2026Article
- Metal-organic frameworks for breath-based sensors: a review.Mikrochimica acta · 2026Review
- Evaluating the VOCORDER device for early disease detection through breath analysis: study protocol for a two-phase clinical study.BMJ open · 2026Article
- Breathprints for Breast Cancer: Evaluating a Non-Invasive Approach to BI-RADS 4 Risk Stratification in a Preliminary Study.Cancers · 2026Article
- The metabolic layer of cognition: integrating metabolomics, breathomics, and systems neuroscience.Frontiers in neuroscience · 2026Review
- Breath by Breath: Navigating the Landscape of Exhaled Breath in Clinical Research and Prospects for the Future.Journal of analytical methods in chemistry · 2026Review
- Breath-based stratification of asthma severity using the MISTRAL platform with integrated HScientific reports · 2025Article
- Volatile Organic Compounds (VOCs) in Neurodegenerative Diseases (NDDs): Diagnostic Potential and Analytical Approaches.Molecules (Basel, Switzerland) · 2025Review
- Systematic comparison of methods for offline breath sampling.Analytical and bioanalytical chemistry · 2025Article
- Breathomics: A Non-Invasive Approach for the Diagnosis of Breast Cancer.Bioengineering (Basel, Switzerland) · 2025Review
- Wearable face mask-attached disposable printed sensor arrays for point-of-need monitoring of alkaline gases in breath.PNAS nexus · 2025Article
- Chemical Nose-Based Non-Invasive Detection of Breast Cancer Using Exhaled Breath.Sensors (Basel, Switzerland) · 2025Article
- Exhaled Breath Analysis Using a Novel Electronic Nose for Different Respiratory Disease Entities.Lung · 2025Article
- Roll-to-roll manufacturing of flexible acetone sensors.PloS one · 2025Article
- Porosity Engineering of Dried Smart Poly(Biomacromolecules · 2024Article
- Breath Fingerprint of Colorectal Cancer Patients Based on the Gas Chromatography-Mass Spectrometry Analysis.International journal of molecular sciences · 2024Article
- Advancing accuracy in breath testing for lung cancer: strategies for improving diagnostic precision in imbalanced data.Respiratory research · 2024Article
- Wireless, battery-free, multifunctional integrated bioelectronics for respiratory pathogens monitoring and severity evaluation.Nature communications · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breath analysis is a promising field with great potential for non-invasive diagnosis of a number of disease states. Analysis of the concentrations of volatile organic compounds (VOCs) in breath with an acceptable accuracy are assessed by means of using analytical techniques with high sensitivity, accuracy, precision, low response time, and low detection limit, which are desirable characteristics for the detection of VOCs in human breath. "Breath fingerprinting", indicative of a specific clinical status, relies on the use of multivariate statistics methods with powerful in-built algorithms. The need for standardisation of sample collection and analysis is the main issue concerning breath analysis, blocking the introduction of breath tests into clinical practice. This review describes recent scientific developments in basic research and clinical applications, namely issues concerning sampling and biochemistry, highlighting the diagnostic potential of breath analysis for disease diagnosis. Several considerations that need to be taken into account in breath analysis are documented here, including the growing need for metabolomics to deal with breath profiles.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.