ArticleJournal of functional biomaterials2011
Micro- and nanoengineering approaches to control stem cell-biomaterial interactions.
Article in Journal of functional biomaterials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 51 citations in OpenAlex.
- Synthesis and use of thermoplastic polymers for tissue engineering purposes.International journal of pharmaceutics: X · 2025Review
- Nanoengineering of gold nanoribbon-embedded isogenic stem cell-derived cardiac organoids.RSC advances · 2023Article
- Constructing a cell microenvironment with biomaterial scaffolds for stem cell therapy.Stem cell research & therapy · 2021Review
- Fabrication Method of a High-Density Co-Culture Tumor-Stroma Platform to Study Cancer Progression.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Review
- Development of three-dimensional articular cartilage construct using silica nano-patterned substrate.PloS one · 2019Article
- Engineering complex tissue-like microgel arrays for evaluating stem cell differentiation.Scientific reports · 2016Article
- Bridging the Gap: From 2D Cell Culture to 3D Microengineered Extracellular Matrices.Advanced healthcare materials · 2015Review
- Stem Cell Differentiation Toward the Myogenic Lineage for Muscle Tissue Regeneration: A Focus on Muscular Dystrophy.Stem cell reviews and reports · 2015Review
- Gene expression profiling and mechanism study of neural stem cells response to surface chemistry.Regenerative biomaterials · 2014Article
- Complex dynamic substrate control: dual-tone hydrogel photoresists allow double-dissociation of topography and modulus.Advanced materials (Deerfield Beach, Fla.) · 2014Article
- Development of functional biomaterials with micro- and nanoscale technologies for tissue engineering and drug delivery applications.Journal of tissue engineering and regenerative medicine · 2014Review
- Fibroblast growth on micro- and nanopatterned surfaces prepared by a novel sol-gel phase separation method.Journal of materials science. Materials in medicine · 2013Article
- Decoupling polymer properties to elucidate mechanisms governing cell behavior.Tissue engineering. Part B, Reviews · 2012Review
- Patterning methods for polymers in cell and tissue engineering.Annals of biomedical engineering · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant progress in controlling stem cell differentiation, it is still difficult to engineer human tissue constructs for transplantation. Recent advances in micro- and nanofabrication techniques have enabled the design of more biomimetic biomaterials that may be used to direct the fate of stem cells. These biomaterials could have a significant impact on the next generation of stem cell based therapies. Here, we highlight the recent progress made by micro- and nanoengineering techniques in the biomaterials field in the context of directing stem cell differentiation. Particular attention is given to the effect of surface topography, chemistry, mechanics and micro- and nanopatterns on the differentiation of embryonic, mesenchymal and neural stem cells.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.