ArticleJournal of functional biomaterials2013
Self-setting calcium orthophosphate formulations.
Article in Journal of functional biomaterials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The trial behind it
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Who cites it
30 citing papers in PubMed.
- Hyaluronan-Containing Injectable Magnesium-Calcium Phosphate Cements Demonstrated Improved Performance, Cytocompatibility, and Ability to Support Osteogenic Differentiation In Vitro.International journal of molecular sciences · 2025Article
- Enhancing bioactivity and mechanical performances of hydroxyapatite-calcium sulfate bone cements for bone repair:RSC advances · 2024Article
- Chitosan scaffolds with mesoporous hydroxyapatite and mesoporous bioactive glass.Progress in biomaterials · 2023Article
- Fast self-curing α-tricalcium phosphate/β-dicalcium silicate composites beneficial for root canal sealing treatment.Heliyon · 2022Article
- Biological analysis of an innovative biodegradable antibiotic eluting bioactive glass/gypsum composite bone cement for treating experimental chronic MRSA osteomyelitis.Journal of pharmaceutical analysis · 2022Article
- Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties.Molecules (Basel, Switzerland) · 2021Article
- Injectable calcium phosphate and styrene-butadiene polymer-based root canal filling material.Asian biomedicine : research, reviews and news · 2021Article
- Microwave-Assisted Fabrication of Mesoporous Silica-Calcium Phosphate Composites for Dental Application.Polymers · 2020Article
- Empirical and theoretical insights into the structural effects of selenite doping in hydroxyapatite and the ensuing inhibition of osteoclasts.Materials science & engineering. C, Materials for biological applications · 2020Article
- Magnetic Calcium Phosphate Cement for Hyperthermia Treatment of Bone Tumors.Materials (Basel, Switzerland) · 2020Article
- Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces.Biofabrication · 2020Article
- Clinical impact of high-profile animal-based research reported in the UK national press.BMJ open science · 2020Article
- Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications.Materials (Basel, Switzerland) · 2019Review
- Calcium phosphate nanoparticles as intrinsic inorganic antimicrobials: In search of the key particle property.Biointerphases · 2019Article
- Smart Injectable Self-Setting Monetite Based Bioceramics for Orthopedic Applications.Materials (Basel, Switzerland) · 2018Article
- Calcium Phosphates as Delivery Systems for Bisphosphonates.Journal of functional biomaterials · 2018Review
- Antimicrobial Hydroxyapatite-Gelatin-Silica Composite Pastes with Tunable Setting Properties.Journal of materials chemistry. B · 2017Article
- Ceramic Biocomposites as Biodegradable Antibiotic Carriers in the Treatment of Bone Infections.Journal of bone and joint infection · 2017Review
- Nonlinear Oscillatory Dynamics of the Hardening of Calcium Phosphate Bone Cements.RSC advances · 2017Article
- One Ion to Rule Them All: Combined Antibacterial, Osteoinductive and Anticancer Properties of Selenite-Incorporated Hydroxyapatite.Journal of materials chemistry. B · 2017Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In early 1980s, researchers discovered self-setting calcium orthophosphate cements, which are bioactive and biodegradable grafting bioceramics in the form of a powder and a liquid. After mixing, both phases form pastes, which set and harden forming either a non-stoichiometric calcium deficient hydroxyapatite or brushite. Since both of them are remarkably biocompartible, bioresorbable and osteoconductive, self-setting calcium orthophosphate formulations appear to be promising bioceramics for bone grafting. Furthermore, such formulations possess excellent molding capabilities, easy manipulation and nearly perfect adaptation to the complex shapes of bone defects, followed by gradual bioresorption and new bone formation. In addition, reinforced formulations have been introduced, which might be described as calcium orthophosphate concretes. The discovery of self-setting properties opened up a new era in the medical application of calcium orthophosphates and many commercial trademarks have been introduced as a result. Currently such formulations are widely used as synthetic bone grafts, with several advantages, such as pourability and injectability. Moreover, their low-temperature setting reactions and intrinsic porosity allow loading by drugs, biomolecules and even cells for tissue engineering purposes. In this review, an insight into the self-setting calcium orthophosphate formulations, as excellent bioceramics suitable for both dental and bone grafting applications, has been provided.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.